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Euglycemic agent-mediated hypothalamic transcriptomic manipulation in the N171-82Q model of Huntington disease is related to their physiological efficacy.
Martin B, Chadwick W, Cong WN, Pantaleo N, Daimon CM, Golden EJ, Becker KG, Wood WH 3rd, Carlson OD, Egan JM, Maudsley S. Martin B, et al. Among authors: chadwick w. J Biol Chem. 2012 Sep 14;287(38):31766-82. doi: 10.1074/jbc.M112.387316. Epub 2012 Jul 20. J Biol Chem. 2012. PMID: 22822065 Free PMC article.
Targeting TNF-alpha receptors for neurotherapeutics.
Chadwick W, Magnus T, Martin B, Keselman A, Mattson MP, Maudsley S. Chadwick W, et al. Trends Neurosci. 2008 Oct;31(10):504-11. doi: 10.1016/j.tins.2008.07.005. Epub 2008 Sep 4. Trends Neurosci. 2008. PMID: 18774186 Free PMC article. No abstract available.
Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease.
Martin B, Golden E, Carlson OD, Pistell P, Zhou J, Kim W, Frank BP, Thomas S, Chadwick WA, Greig NH, Bates GP, Sathasivam K, Bernier M, Maudsley S, Mattson MP, Egan JM. Martin B, et al. Among authors: chadwick wa. Diabetes. 2009 Feb;58(2):318-28. doi: 10.2337/db08-0799. Epub 2008 Nov 4. Diabetes. 2009. PMID: 18984744 Free PMC article.
66 results