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IDO is a nodal pathogenic driver of lung cancer and metastasis development.
Smith C, Chang MY, Parker KH, Beury DW, DuHadaway JB, Flick HE, Boulden J, Sutanto-Ward E, Soler AP, Laury-Kleintop LD, Mandik-Nayak L, Metz R, Ostrand-Rosenberg S, Prendergast GC, Muller AJ. Smith C, et al. Among authors: duhadaway jb. Cancer Discov. 2012 Aug;2(8):722-35. doi: 10.1158/2159-8290.CD-12-0014. Epub 2012 Jul 19. Cancer Discov. 2012. PMID: 22822050 Free PMC article.
Bin3 deletion causes cataracts and increased susceptibility to lymphoma during aging.
Ramalingam A, Duhadaway JB, Sutanto-Ward E, Wang Y, Dinchuk J, Huang M, Donover PS, Boulden J, McNally LM, Soler AP, Muller AJ, Duncan MK, Prendergast GC. Ramalingam A, et al. Among authors: duhadaway jb. Cancer Res. 2008 Mar 15;68(6):1683-90. doi: 10.1158/0008-5472.CAN-07-6072. Cancer Res. 2008. PMID: 18339847
Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion.
Muller AJ, DuHadaway JB, Chang MY, Ramalingam A, Sutanto-Ward E, Boulden J, Soler AP, Mandik-Nayak L, Gilmour SK, Prendergast GC. Muller AJ, et al. Among authors: duhadaway jb. Cancer Immunol Immunother. 2010 Nov;59(11):1655-63. doi: 10.1007/s00262-010-0891-4. Epub 2010 Jul 17. Cancer Immunol Immunother. 2010. PMID: 20640572 Free PMC article.
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