Lau KS - Search Results

1

BAY61-3606 affects the viability of colon cancer cells in a genotype-directed manner.

Lau KS, Zhang T, Kendall KR, Lauffenburger D, Gray NS, Haigis KM. Lau KS, et al. PLoS One. 2012;7(7):e41343. doi: 10.1371/journal.pone.0041343. Epub 2012 Jul 18. PLoS One. 2012. PMID: 22815993 Free PMC article.

2

Non-redundancy within the RAS oncogene family: insights into mutational disparities in cancer.

Lau KS, Haigis KM. Lau KS, et al. Mol Cells. 2009 Oct 31;28(4):315-20. doi: 10.1007/s10059-009-0143-7. Epub 2009 Sep 30. Mol Cells. 2009. PMID: 19812895 Free PMC article. Review.

3

In vivo systems analysis identifies spatial and temporal aspects of the modulation of TNF-α-induced apoptosis and proliferation by MAPKs.

Lau KS, Juchheim AM, Cavaliere KR, Philips SR, Lauffenburger DA, Haigis KM. Lau KS, et al. Sci Signal. 2011 Mar 22;4(165):ra16. doi: 10.1126/scisignal.2001338. Sci Signal. 2011. PMID: 21427409 Free PMC article.

4

Multi-scale in vivo systems analysis reveals the influence of immune cells on TNF-α-induced apoptosis in the intestinal epithelium.

Lau KS, Cortez-Retamozo V, Philips SR, Pittet MJ, Lauffenburger DA, Haigis KM. Lau KS, et al. PLoS Biol. 2012;10(9):e1001393. doi: 10.1371/journal.pbio.1001393. Epub 2012 Sep 25. PLoS Biol. 2012. PMID: 23055830 Free PMC article.

5

Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice.

Miraldi ER, Sharfi H, Friedline RH, Johnson H, Zhang T, Lau KS, Ko HJ, Curran TG, Haigis KM, Yaffe MB, Bonneau R, Lauffenburger DA, Kahn BB, Kim JK, Neel BG, Saghatelian A, White FM. Miraldi ER, et al. Among authors: lau ks. Integr Biol (Camb). 2013 Jul 24;5(7):940-63. doi: 10.1039/c3ib40013a. Epub 2013 May 20. Integr Biol (Camb). 2013. PMID: 23685806 Free PMC article.

6

Network analysis of differential Ras isoform mutation effects on intestinal epithelial responses to TNF-α.

Lau KS, Schrier SB, Gierut J, Lyons J, Lauffenburger DA, Haigis KM. Lau KS, et al. Integr Biol (Camb). 2013 Nov;5(11):1355-65. doi: 10.1039/c3ib40062j. Epub 2013 Oct 2. Integr Biol (Camb). 2013. PMID: 24084984 Free PMC article.

7

Network-level effects of kinase inhibitors modulate TNF-α-induced apoptosis in the intestinal epithelium.

Gierut JJ, Wood LB, Lau KS, Lin YJ, Genetti C, Samatar AA, Lauffenburger DA, Haigis KM. Gierut JJ, et al. Among authors: lau ks. Sci Signal. 2015 Dec 15;8(407):ra129. doi: 10.1126/scisignal.aac7235. Sci Signal. 2015. PMID: 26671150 Free PMC article.

8

An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease.

Brubaker DK, Kumar MP, Chiswick EL, Gregg C, Starchenko A, Vega PN, Southard-Smith AN, Simmons AJ, Scoville EA, Coburn LA, Wilson KT, Lau KS, Lauffenburger DA. Brubaker DK, et al. Among authors: lau ks. Sci Signal. 2020 Aug 4;13(643):eaay3258. doi: 10.1126/scisignal.aay3258. Sci Signal. 2020. PMID: 32753478 Free PMC article.

9

Cancer-Associated Fibroblasts and Squamous Epithelial Cells Constitute a Unique Microenvironment in a Mouse Model of Inflammation-Induced Colon Cancer.

Vega PN, Nilsson A, Kumar MP, Niitsu H, Simmons AJ, Ro J, Wang J, Chen Z, Joughin BA, Li W, McKinley ET, Liu Q, Roland JT, Washington MK, Coffey RJ, Lauffenburger DA, Lau KS. Vega PN, et al. Among authors: lau ks. Front Oncol. 2022 May 4;12:878920. doi: 10.3389/fonc.2022.878920. eCollection 2022. Front Oncol. 2022. PMID: 35600339 Free PMC article.

10

Oncogenic K-Ras suppresses global miRNA function.

Shui B, Beyett TS, Chen Z, Li X, La Rocca G, Gazlay WM, Eck MJ, Lau KS, Ventura A, Haigis KM. Shui B, et al. Among authors: lau ks. Mol Cell. 2023 Jul 20;83(14):2509-2523.e13. doi: 10.1016/j.molcel.2023.06.008. Epub 2023 Jul 3. Mol Cell. 2023. PMID: 37402366 Free PMC article.

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