Grabow S - Search Results

1

Prophylactic treatment with the BH3 mimetic ABT-737 impedes Myc-driven lymphomagenesis in mice.

Kelly PN, Grabow S, Delbridge AR, Adams JM, Strasser A. Kelly PN, et al. Among authors: grabow s. Cell Death Differ. 2013 Jan;20(1):57-63. doi: 10.1038/cdd.2012.92. Epub 2012 Jul 20. Cell Death Differ. 2013. PMID: 22814621 Free PMC article.

2

Pharmacological blockade of Bcl-2, Bcl-x(L) and Bcl-w by the BH3 mimetic ABT-737 has only minor impact on tumour development in p53-deficient mice.

Grabow S, Waring P, Happo L, Cook M, Mason KD, Kelly PN, Strasser A. Grabow S, et al. Cell Death Differ. 2012 Apr;19(4):623-32. doi: 10.1038/cdd.2011.133. Epub 2011 Oct 14. Cell Death Differ. 2012. PMID: 21997189 Free PMC article.

3

Functional antagonism between pro-apoptotic BIM and anti-apoptotic BCL-XL in MYC-induced lymphomagenesis.

Delbridge AR, Grabow S, Bouillet P, Adams JM, Strasser A. Delbridge AR, et al. Among authors: grabow s. Oncogene. 2015 Apr 2;34(14):1872-6. doi: 10.1038/onc.2014.132. Epub 2014 May 26. Oncogene. 2015. PMID: 24858047

4

Endogenous Bcl-xL is essential for Myc-driven lymphomagenesis in mice.

Kelly PN, Grabow S, Delbridge AR, Strasser A, Adams JM. Kelly PN, et al. Among authors: grabow s. Blood. 2011 Dec 8;118(24):6380-6. doi: 10.1182/blood-2011-07-367672. Epub 2011 Oct 12. Blood. 2011. PMID: 21998213 Free PMC article.

5

Critical B-lymphoid cell intrinsic role of endogenous MCL-1 in c-MYC-induced lymphomagenesis.

Grabow S, Kelly GL, Delbridge AR, Kelly PN, Bouillet P, Adams JM, Strasser A. Grabow S, et al. Cell Death Dis. 2016 Mar 10;7(3):e2132. doi: 10.1038/cddis.2016.43. Cell Death Dis. 2016. PMID: 26962682 Free PMC article.

6

The BH3-only proteins BIM and PUMA are not critical for the reticulocyte apoptosis caused by loss of the pro-survival protein BCL-XL.

Delbridge AR, Aubrey BJ, Hyland C, Bernardini JP, Di Rago L, Garnier JM, Lessene G, Strasser A, Alexander WS, Grabow S. Delbridge AR, et al. Among authors: grabow s. Cell Death Dis. 2017 Jul 6;8(7):e2914. doi: 10.1038/cddis.2017.304. Cell Death Dis. 2017. PMID: 28682312 Free PMC article.

7

Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies.

Delbridge AR, Grabow S, Strasser A, Vaux DL. Delbridge AR, et al. Among authors: grabow s. Nat Rev Cancer. 2016 Feb;16(2):99-109. doi: 10.1038/nrc.2015.17. Nat Rev Cancer. 2016. PMID: 26822577 Review.

8

Loss of a Single Mcl-1 Allele Inhibits MYC-Driven Lymphomagenesis by Sensitizing Pro-B Cells to Apoptosis.

Grabow S, Delbridge AR, Aubrey BJ, Vandenberg CJ, Strasser A. Grabow S, et al. Cell Rep. 2016 Mar 15;14(10):2337-47. doi: 10.1016/j.celrep.2016.02.039. Epub 2016 Mar 3. Cell Rep. 2016. PMID: 26947081 Free article.

9

Loss of BIM augments resistance of ATM-deficient thymocytes to DNA damage-induced apoptosis but does not accelerate lymphoma development.

Delbridge AR, Grabow S, Strasser A. Delbridge AR, et al. Among authors: grabow s. Cell Death Differ. 2017 Nov;24(11):1987-1988. doi: 10.1038/cdd.2017.138. Epub 2017 Sep 8. Cell Death Differ. 2017. PMID: 28885618 Free PMC article. No abstract available.

10

BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells.

Moujalled D, Southon AG, Saleh E, Brinkmann K, Ke F, Iliopoulos M, Cross RS, Jenkins MR, Nhu D, Wang Z, Shi MX, Kluck RM, Lessene G, Grabow S, Bush AI, Strasser A. Moujalled D, et al. Among authors: grabow s. Cell Death Differ. 2022 Jul;29(7):1335-1348. doi: 10.1038/s41418-022-00977-2. Epub 2022 Mar 24. Cell Death Differ. 2022. PMID: 35332309 Free PMC article.

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