Richard JP - Search Results

1

Proton transfer from C-6 of uridine 5'-monophosphate catalyzed by orotidine 5'-monophosphate decarboxylase: formation and stability of a vinyl carbanion intermediate and the effect of a 5-fluoro substituent.

Tsang WY, Wood BM, Wong FM, Wu W, Gerlt JA, Amyes TL, Richard JP. Tsang WY, et al. Among authors: richard jp. J Am Chem Soc. 2012 Sep 5;134(35):14580-94. doi: 10.1021/ja3058474. Epub 2012 Aug 21. J Am Chem Soc. 2012. PMID: 22812629 Free PMC article.

2

Structure-reactivity relationships for beta-galactosidase (Escherichia coli, lac Z). 3. Evidence that Glu-461 participates in Brønsted acid-base catalysis of beta-D-galactopyranosyl group transfer.

Richard JP, Huber RE, Lin S, Heo C, Amyes TL. Richard JP, et al. Biochemistry. 1996 Sep 24;35(38):12377-86. doi: 10.1021/bi961028j. Biochemistry. 1996. PMID: 8823173

3

Structure-reactivity relationships for beta-galactosidase (Escherichia coli, lac Z). 4. Mechanism for reaction of nucleophiles with the galactosyl-enzyme intermediates of E461G and E461Q beta-galactosidases.

Richard JP, Huber RE, Heo C, Amyes TL, Lin S. Richard JP, et al. Biochemistry. 1996 Sep 24;35(38):12387-401. doi: 10.1021/bi961029b. Biochemistry. 1996. PMID: 8823174

4

Dynamics for reaction of an ion pair in aqueous solution: reactivity of carboxylate anions in bimolecular carbocation-nucleophile addition and unimolecular ion pair collapse.

Tsuji Y, Mori T, Richard JP, Amyes TL, Fujio M, Tsuno Y. Tsuji Y, et al. Among authors: richard jp. Org Lett. 2001 Apr 19;3(8):1237-40. doi: 10.1021/ol015706s. Org Lett. 2001. PMID: 11348203

5

What is the stabilizing interaction with nucleophilic solvents in the transition state for solvolysis of tertiary derivatives: nucleophilic solvent participation or nucleophilic solvation?

Richard JP, Toteva MM, Amyes TL. Richard JP, et al. Org Lett. 2001 Jul 12;3(14):2225-8. doi: 10.1021/ol016103j. Org Lett. 2001. PMID: 11440585

6

Mechanistic imperatives for aldose-ketose isomerization in water: specific, general base- and metal ion-catalyzed isomerization of glyceraldehyde with proton and hydride transfer.

Nagorski RW, Richard JP. Nagorski RW, et al. Among authors: richard jp. J Am Chem Soc. 2001 Feb 7;123(5):794-802. doi: 10.1021/ja003433a. J Am Chem Soc. 2001. PMID: 11456612

7

Glycine enolates: the large effect of iminium ion formation on alpha-amino carbon acidity.

Rios A, Crugeiras J, Amyes TL, Richard JP. Rios A, et al. Among authors: richard jp. J Am Chem Soc. 2001 Aug 15;123(32):7949-50. doi: 10.1021/ja016250c. J Am Chem Soc. 2001. PMID: 11493086 No abstract available.

8

Keto-enol/enolate equilibria in the N-acetylamino-p-methylacetophenone system. Effect of a beta-nitrogen substituent.

Chiang Y, Griesbeck AG, Heckroth H, Hellrung B, Kresge AJ, Meng Q, O'Donoghue AC, Richard JP, Wirz J. Chiang Y, et al. Among authors: richard jp. J Am Chem Soc. 2001 Sep 19;123(37):8979-84. doi: 10.1021/ja0107529. J Am Chem Soc. 2001. PMID: 11552805

9

Contribution of phosphate intrinsic binding energy to the enzymatic rate acceleration for triosephosphate isomerase.

Amyes TL, O'Donoghue AC, Richard JP. Amyes TL, et al. Among authors: richard jp. J Am Chem Soc. 2001 Nov 14;123(45):11325-6. doi: 10.1021/ja016754a. J Am Chem Soc. 2001. PMID: 11697989 No abstract available.

10

Proton transfer at carbon.

Richard JP, Amyes TL. Richard JP, et al. Curr Opin Chem Biol. 2001 Dec;5(6):626-33. doi: 10.1016/s1367-5931(01)00258-7. Curr Opin Chem Biol. 2001. PMID: 11738171 Review.

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