Amyes TL - Search Results

1

Proton transfer from C-6 of uridine 5'-monophosphate catalyzed by orotidine 5'-monophosphate decarboxylase: formation and stability of a vinyl carbanion intermediate and the effect of a 5-fluoro substituent.

Tsang WY, Wood BM, Wong FM, Wu W, Gerlt JA, Amyes TL, Richard JP. Tsang WY, et al. Among authors: amyes tl. J Am Chem Soc. 2012 Sep 5;134(35):14580-94. doi: 10.1021/ja3058474. Epub 2012 Aug 21. J Am Chem Soc. 2012. PMID: 22812629 Free PMC article.

2

Formation and stability of enolates of acetamide and acetate anion: an Eigen plot for proton transfer at alpha-carbonyl carbon.

Richard JP, Williams G, O'Donoghue AC, Amyes TL. Richard JP, et al. Among authors: amyes tl. J Am Chem Soc. 2002 Mar 27;124(12):2957-68. doi: 10.1021/ja0125321. J Am Chem Soc. 2002. PMID: 11902887

3

Formation and stability of peptide enolates in aqueous solution.

Rios A, Richard JP, Amyes TL. Rios A, et al. Among authors: amyes tl. J Am Chem Soc. 2002 Jul 17;124(28):8251-9. doi: 10.1021/ja026267a. J Am Chem Soc. 2002. PMID: 12105903

4

Substituent effects on carbocation stability: the pK(R) for p-quinone methide.

Toteva MM, Moran M, Amyes TL, Richard JP. Toteva MM, et al. Among authors: amyes tl. J Am Chem Soc. 2003 Jul 23;125(29):8814-9. doi: 10.1021/ja029588v. J Am Chem Soc. 2003. PMID: 12862476

5

Formation and stability of N-heterocyclic carbenes in water: the carbon acid pKa of imidazolium cations in aqueous solution.

Amyes TL, Diver ST, Richard JP, Rivas FM, Toth K. Amyes TL, et al. J Am Chem Soc. 2004 Apr 7;126(13):4366-74. doi: 10.1021/ja039890j. J Am Chem Soc. 2004. PMID: 15053626

6

Claisen-type addition of glycine to pyridoxal in water.

Toth K, Amyes TL, Richard JP, Malthouse JP, NíBeilliú ME. Toth K, et al. Among authors: amyes tl. J Am Chem Soc. 2004 Sep 1;126(34):10538-9. doi: 10.1021/ja047501v. J Am Chem Soc. 2004. PMID: 15327301

7

Activation of orotidine 5'-monophosphate decarboxylase by phosphite dianion: the whole substrate is the sum of two parts.

Amyes TL, Richard JP, Tait JJ. Amyes TL, et al. J Am Chem Soc. 2005 Nov 16;127(45):15708-9. doi: 10.1021/ja055493s. J Am Chem Soc. 2005. PMID: 16277505

8

Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate.

Toth K, Amyes TL, Wood BM, Chan K, Gerlt JA, Richard JP. Toth K, et al. Among authors: amyes tl. J Am Chem Soc. 2007 Oct 31;129(43):12946-7. doi: 10.1021/ja076222f. Epub 2007 Oct 5. J Am Chem Soc. 2007. PMID: 17918849 Free PMC article. No abstract available.

9

Formation and stability of a vinyl carbanion at the active site of orotidine 5'-monophosphate decarboxylase: pKa of the C-6 proton of enzyme-bound UMP.

Amyes TL, Wood BM, Chan K, Gerlt JA, Richard JP. Amyes TL, et al. J Am Chem Soc. 2008 Feb 6;130(5):1574-5. doi: 10.1021/ja710384t. Epub 2008 Jan 11. J Am Chem Soc. 2008. PMID: 18186641 Free PMC article.

10

Dissecting the total transition state stabilization provided by amino acid side chains at orotidine 5'-monophosphate decarboxylase: a two-part substrate approach.

Barnett SA, Amyes TL, Wood BM, Gerlt JA, Richard JP. Barnett SA, et al. Among authors: amyes tl. Biochemistry. 2008 Jul 29;47(30):7785-7. doi: 10.1021/bi800939k. Epub 2008 Jul 4. Biochemistry. 2008. PMID: 18598058 Free PMC article.

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