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A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C.
Lange CM, Bibert S, Kutalik Z, Burgisser P, Cerny A, Dufour JF, Geier A, Gerlach TJ, Heim MH, Malinverni R, Negro F, Regenass S, Badenhoop K, Bojunga J, Sarrazin C, Zeuzem S, Müller T, Berg T, Bochud PY, Moradpour D; Swiss Hepatitis C Cohort Study Group. Lange CM, et al. Among authors: negro f. PLoS One. 2012;7(7):e40159. doi: 10.1371/journal.pone.0040159. Epub 2012 Jul 12. PLoS One. 2012. PMID: 22808108 Free PMC article.
Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.
Lange CM, Kutalik Z, Morikawa K, Bibert S, Cerny A, Dollenmaier G, Dufour JF, Gerlach TJ, Heim MH, Malinverni R, Müllhaupt B, Negro F, Moradpour D, Bochud PY; Swiss Hepatitis C Cohort Study Group. Lange CM, et al. Among authors: negro f. Hepatology. 2012 Apr;55(4):1038-47. doi: 10.1002/hep.24787. Epub 2012 Feb 9. Hepatology. 2012. PMID: 22095909
IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes.
Bochud PY, Bibert S, Kutalik Z, Patin E, Guergnon J, Nalpas B, Goossens N, Kuske L, Müllhaupt B, Gerlach T, Heim MH, Moradpour D, Cerny A, Malinverni R, Regenass S, Dollenmaier G, Hirsch H, Martinetti G, Gorgiewski M, Bourlière M, Poynard T, Theodorou I, Abel L, Pol S, Dufour JF, Negro F; Swiss Hepatitis C Cohort Study Group; ANRS HC EP 26 Genoscan Study Group. Bochud PY, et al. Among authors: negro f. Hepatology. 2012 Feb;55(2):384-94. doi: 10.1002/hep.24678. Epub 2011 Dec 16. Hepatology. 2012. PMID: 22180014
Genetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development.
Lange CM, Miki D, Ochi H, Nischalke HD, Bojunga J, Bibert S, Morikawa K, Gouttenoire J, Cerny A, Dufour JF, Gorgievski-Hrisoho M, Heim MH, Malinverni R, Müllhaupt B, Negro F, Semela D, Kutalik Z, Müller T, Spengler U, Berg T, Chayama K, Moradpour D, Bochud PY; Hiroshima Liver Study Group; Swiss Hepatitis C Cohort Study Group. Lange CM, et al. Among authors: negro f. PLoS One. 2013 May 29;8(5):e64053. doi: 10.1371/journal.pone.0064053. Print 2013. PLoS One. 2013. PMID: 23734184 Free PMC article.
Elderly age is not a negative predictive factor for virological response to therapy with pegylated interferon-α and ribavirin in chronic hepatitis C virus patients.
Frei P, Leucht AK, Held U, Kofmehl R, Manser CN, Schmitt J, Mertens J, Rau M, Baur K, Gerlach T, Negro F, Heim M, Moradpour D, Cerny A, Dufour JF, Müllhaupt B, Geier A; Swiss Hepatitis C Cohort Study Group. Frei P, et al. Among authors: negro f. Liver Int. 2014 Apr;34(4):551-7. doi: 10.1111/liv.12279. Epub 2013 Aug 29. Liver Int. 2014. PMID: 24034338
Genotype 3 is associated with accelerated fibrosis progression in chronic hepatitis C.
Bochud PY, Cai T, Overbeck K, Bochud M, Dufour JF, Müllhaupt B, Borovicka J, Heim M, Moradpour D, Cerny A, Malinverni R, Francioli P, Negro F; Swiss Hepatitis C Cohort Study Group. Bochud PY, et al. Among authors: negro f. J Hepatol. 2009 Oct;51(4):655-66. doi: 10.1016/j.jhep.2009.05.016. Epub 2009 Jun 6. J Hepatol. 2009. PMID: 19665246
Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study.
Rauch A, Kutalik Z, Descombes P, Cai T, Di Iulio J, Mueller T, Bochud M, Battegay M, Bernasconi E, Borovicka J, Colombo S, Cerny A, Dufour JF, Furrer H, Günthard HF, Heim M, Hirschel B, Malinverni R, Moradpour D, Müllhaupt B, Witteck A, Beckmann JS, Berg T, Bergmann S, Negro F, Telenti A, Bochud PY; Swiss Hepatitis C Cohort Study; Swiss HIV Cohort Study. Rauch A, et al. Among authors: negro f. Gastroenterology. 2010 Apr;138(4):1338-45, 1345.e1-7. doi: 10.1053/j.gastro.2009.12.056. Epub 2010 Jan 11. Gastroenterology. 2010. PMID: 20060832
Treatment of hepatitis C in HCV mono-infected and in HIV-HCV co-infected patients: an open-labelled comparison study.
Gonvers JJ, Heim MH, Cavassini M, Müllhaupt B, Genné D, Bernasconi E, Borovicka J, Cerny A, Chave JP, Chuard C, Dufour F, Dutoit V, Malinverni R, Monnat M, Negro F, Troilliet N, Oneta C. Gonvers JJ, et al. Among authors: negro f. Swiss Med Wkly. 2010 Jul 19;140:w13055. doi: 10.4414/smw.2010.13055. eCollection 2010. Swiss Med Wkly. 2010. PMID: 20648398 Free article. Clinical Trial.
[Hepatitis D: forgotten but not gone].
Moradpour D, Negro F. Moradpour D, et al. Among authors: negro f. Rev Med Suisse. 2010 Sep 8;6(261):1656-9. Rev Med Suisse. 2010. PMID: 20939399 French.
678 results