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Discovery of 3-(5-chloro-2-furoyl)-3,7-diazabicyclo[3.3.0]octane (TC-6683, AZD1446), a novel highly selective α4β2 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders.
Mazurov AA, Miao L, Bhatti BS, Strachan JP, Akireddy S, Murthy S, Kombo D, Xiao YD, Hammond P, Zhang J, Hauser TA, Jordan KG, Miller CH, Speake JD, Gatto GJ, Yohannes D. Mazurov AA, et al. Among authors: murthy s. J Med Chem. 2012 Nov 8;55(21):9181-94. doi: 10.1021/jm3006542. Epub 2012 Jul 27. J Med Chem. 2012. PMID: 22793665
Identification and pharmacological characterization of 3,6-diazabicyclo[3.1.1]heptane-3-carboxamides as novel ligands for the α4β2 and α6/α3β2β3 nicotinic acetylcholine receptors (nAChRs).
Strachan JP, Kombo DC, Mazurov A, Heemstra R, Bhatti BS, Akireddy R, Murthy S, Miao L, Jett JE, Speake J, Bencherif M. Strachan JP, et al. Among authors: murthy s. Eur J Med Chem. 2014 Oct 30;86:60-74. doi: 10.1016/j.ejmech.2014.08.019. Epub 2014 Aug 7. Eur J Med Chem. 2014. PMID: 25147147
Eligibility Criteria of Randomized Clinical Trials in Critical Care Medicine.
Heirali A, Heybati K, Sereeyotin J, Khan F, Yarnell C, Krewulak K, Murthy S, Burns KEA, Fowler R, Fiest K, Mehta S; Canadian Critical Care Trials Group. Heirali A, et al. Among authors: murthy s. JAMA Netw Open. 2025 Jan 2;8(1):e2454944. doi: 10.1001/jamanetworkopen.2024.54944. JAMA Netw Open. 2025. PMID: 39821399
Metabolomic in severe traumatic brain injury: exploring primary, secondary injuries, diagnosis, and severity.
Banoei MM, Hutchison J, Panenka W, Wong A, Wishart DS, Winston BW; Canadian Biobank and Database for Traumatic Brain Injury (CanTBI) study investigators; Canadian Critical Care Translational Biology Group (CCCTBG); Canadian Traumatic Brain Injury Research Consortium (CTRC). Banoei MM, et al. Crit Care. 2025 Jan 15;29(1):26. doi: 10.1186/s13054-025-05258-1. Crit Care. 2025. PMID: 39815318 Free PMC article.
An Elusive Diagnosis of Castleman Disease.
Rifai Y, Bhagat R, Murthy S, Bribriesco A. Rifai Y, et al. Among authors: murthy s. Ann Thorac Surg Short Rep. 2024 Mar 27;2(3):548-551. doi: 10.1016/j.atssr.2024.02.018. eCollection 2024 Sep. Ann Thorac Surg Short Rep. 2024. PMID: 39790424 Free PMC article.
Machine Learning Models for 3-Month Outcome Prediction Using Radiomics of Intracerebral Hemorrhage and Perihematomal Edema from Admission Head Computed Tomography (CT).
Dierksen F, Sommer JK, Tran AT, Lin H, Haider SP, Maier IL, Aneja S, Sanelli PC, Malhotra A, Qureshi AI, Claassen J, Park S, Murthy SB, Falcone GJ, Sheth KN, Payabvash S. Dierksen F, et al. Among authors: murthy sb. Diagnostics (Basel). 2024 Dec 16;14(24):2827. doi: 10.3390/diagnostics14242827. Diagnostics (Basel). 2024. PMID: 39767188 Free PMC article.
Ischemic Stroke Prevention in Patients Atrial Fibrillation and a Recent Ischemic Stroke, TIA, or Intracranial Hemorrhage; a World Stroke Organisation (WSO) Scientific Statement.
Sposato LA, Cameron A, Johansen MC, Katan M, Murthy SB, Schachter M, Sur N, Yaghi S, Aspberg S, Caso V, Hsieh CY, Hilz M, Nucera A, Seiffge DJ, Sheppard M, Martins SO, Bahit MC, Scheitz JF, Shoamanesh A. Sposato LA, et al. Among authors: murthy sb. Int J Stroke. 2024 Dec 24:17474930241312649. doi: 10.1177/17474930241312649. Online ahead of print. Int J Stroke. 2024. PMID: 39719823 Review.
2,473 results