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Aldosterone inactivates the endothelin-B receptor via a cysteinyl thiol redox switch to decrease pulmonary endothelial nitric oxide levels and modulate pulmonary arterial hypertension.
Maron BA, Zhang YY, White K, Chan SY, Handy DE, Mahoney CE, Loscalzo J, Leopold JA. Maron BA, et al. Among authors: zhang yy. Circulation. 2012 Aug 21;126(8):963-74. doi: 10.1161/CIRCULATIONAHA.112.094722. Epub 2012 Jul 11. Circulation. 2012. PMID: 22787113 Free PMC article.
Heparin reacts with and inactivates nitric oxide.
Upchurch GR Jr, Goodman DG, Willoughby SR, Zhang YY, Welch GN, Freedman JE, Ye S, Costello CE, Loscalzo J. Upchurch GR Jr, et al. Among authors: zhang yy. J Cardiovasc Pharmacol Ther. 2001 Apr;6(2):163-73. doi: 10.1177/107424840100600208. J Cardiovasc Pharmacol Ther. 2001. PMID: 11509923
3,240 results