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Aldosterone inactivates the endothelin-B receptor via a cysteinyl thiol redox switch to decrease pulmonary endothelial nitric oxide levels and modulate pulmonary arterial hypertension.
Maron BA, Zhang YY, White K, Chan SY, Handy DE, Mahoney CE, Loscalzo J, Leopold JA. Maron BA, et al. Among authors: loscalzo j. Circulation. 2012 Aug 21;126(8):963-74. doi: 10.1161/CIRCULATIONAHA.112.094722. Epub 2012 Jul 11. Circulation. 2012. PMID: 22787113 Free PMC article.
Methylene blue reverses endotoxin-induced hypotension.
Keaney JF Jr, Puyana JC, Francis S, Loscalzo JF, Stamler JS, Loscalzo J. Keaney JF Jr, et al. Among authors: loscalzo j, loscalzo jf. Circ Res. 1994 Jun;74(6):1121-5. doi: 10.1161/01.res.74.6.1121. Circ Res. 1994. PMID: 8187278
851 results