Brown PA - Search Results

1

Reaping the benefits of recent advances for adults with acute lymphoblastic leukemia.

Brown PA, Alvarnas JC. Brown PA, et al. J Natl Compr Canc Netw. 2012 Jul 1;10(7):800-1. doi: 10.6004/jnccn.2012.0083. J Natl Compr Canc Netw. 2012. PMID: 22773795 Free PMC article. No abstract available.

2

FLT3 inhibition selectively kills childhood acute lymphoblastic leukemia cells with high levels of FLT3 expression.

Brown P, Levis M, Shurtleff S, Campana D, Downing J, Small D. Brown P, et al. Blood. 2005 Jan 15;105(2):812-20. doi: 10.1182/blood-2004-06-2498. Epub 2004 Sep 16. Blood. 2005. PMID: 15374878 Free article.

3

IMC-EB10, an anti-FLT3 monoclonal antibody, prolongs survival and reduces nonobese diabetic/severe combined immunodeficient engraftment of some acute lymphoblastic leukemia cell lines and primary leukemic samples.

Piloto O, Nguyen B, Huso D, Kim KT, Li Y, Witte L, Hicklin DJ, Brown P, Small D. Piloto O, et al. Cancer Res. 2006 May 1;66(9):4843-51. doi: 10.1158/0008-5472.CAN-06-0018. Cancer Res. 2006. PMID: 16651440

4

Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting.

Schafer E, Irizarry R, Negi S, McIntyre E, Small D, Figueroa ME, Melnick A, Brown P. Schafer E, et al. Blood. 2010 Jun 10;115(23):4798-809. doi: 10.1182/blood-2009-09-243634. Epub 2010 Mar 9. Blood. 2010. PMID: 20215641 Free PMC article.

5

Acute lymphoblastic leukemia.

Alvarnas JC, Brown PA, Aoun P, Ballen KK, Bellam N, Blum W, Boyer MW, Carraway HE, Coccia PF, Coutre SE, Cultrera J, Damon LE, DeAngelo DJ, Douer D, Frangoul H, Frankfurt O, Goorha S, Millenson MM, O'Brien S, Petersdorf SH, Rao AV, Terezakis S, Uy G, Wetzler M, Zelenetz AD, Naganuma M, Gregory KM; National Comprehensive Cancer Network. Alvarnas JC, et al. Among authors: brown pa. J Natl Compr Canc Netw. 2012 Jul 1;10(7):858-914. doi: 10.6004/jnccn.2012.0089. J Natl Compr Canc Netw. 2012. PMID: 22773801

6

MLL-rearranged acute lymphoblastic leukaemia stem cell interactions with bone marrow stroma promote survival and therapeutic resistance that can be overcome with CXCR4 antagonism.

Sison EA, Rau RE, McIntyre E, Li L, Small D, Brown P. Sison EA, et al. Br J Haematol. 2013 Mar;160(6):785-97. doi: 10.1111/bjh.12205. Epub 2013 Jan 7. Br J Haematol. 2013. PMID: 23294096 Free PMC article.

7

A phase I study of EZN-3042, a novel survivin messenger ribonucleic acid (mRNA) antagonist, administered in combination with chemotherapy in children with relapsed acute lymphoblastic leukemia (ALL): a report from the therapeutic advances in childhood leukemia and lymphoma (TACL) consortium.

Raetz EA, Morrison D, Romanos-Sirakis E, Gaynon P, Sposto R, Bhojwani D, Bostrom BC, Brown P, Eckroth E, Cassar J, Malvar J, Buchbinder A, Carroll WL. Raetz EA, et al. J Pediatr Hematol Oncol. 2014 Aug;36(6):458-63. doi: 10.1097/MPH.0b013e3182a8f58f. J Pediatr Hematol Oncol. 2014. PMID: 24276047 Free PMC article. Clinical Trial.

8

FLT3 kinase inhibitor TTT-3002 overcomes both activating and drug resistance mutations in FLT3 in acute myeloid leukemia.

Ma HS, Nguyen B, Duffield AS, Li L, Galanis A, Williams AB, Brown PA, Levis MJ, Leahy DJ, Small D. Ma HS, et al. Among authors: brown pa. Cancer Res. 2014 Sep 15;74(18):5206-17. doi: 10.1158/0008-5472.CAN-14-1028. Epub 2014 Jul 24. Cancer Res. 2014. PMID: 25060518 Free PMC article.

9

Plerixafor as a chemosensitizing agent in pediatric acute lymphoblastic leukemia: efficacy and potential mechanisms of resistance to CXCR4 inhibition.

Sison EA, Magoon D, Li L, Annesley CE, Rau RE, Small D, Brown P. Sison EA, et al. Oncotarget. 2014 Oct 15;5(19):8947-58. doi: 10.18632/oncotarget.2407. Oncotarget. 2014. PMID: 25333254 Free PMC article.

10

Treatment of pediatric acute lymphoblastic leukemia.

Cooper SL, Brown PA. Cooper SL, et al. Among authors: brown pa. Pediatr Clin North Am. 2015 Feb;62(1):61-73. doi: 10.1016/j.pcl.2014.09.006. Epub 2014 Oct 18. Pediatr Clin North Am. 2015. PMID: 25435112 Free PMC article. Review.

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