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Page 1
Interleukin-23 is sufficient to induce rapid de novo gut tumorigenesis, independent of carcinogens, through activation of innate lymphoid cells.
Chan IH, Jain R, Tessmer MS, Gorman D, Mangadu R, Sathe M, Vives F, Moon C, Penaflor E, Turner S, Ayanoglu G, Chang C, Basham B, Mumm JB, Pierce RH, Yearley JH, McClanahan TK, Phillips JH, Cua DJ, Bowman EP, Kastelein RA, LaFace D. Chan IH, et al. Among authors: pierce rh. Mucosal Immunol. 2014 Jul;7(4):842-56. doi: 10.1038/mi.2013.101. Epub 2013 Nov 27. Mucosal Immunol. 2014. PMID: 24280935 Free article.
IL-33 induces IL-13-dependent cutaneous fibrosis.
Rankin AL, Mumm JB, Murphy E, Turner S, Yu N, McClanahan TK, Bourne PA, Pierce RH, Kastelein R, Pflanz S. Rankin AL, et al. Among authors: pierce rh. J Immunol. 2010 Feb 1;184(3):1526-35. doi: 10.4049/jimmunol.0903306. Epub 2009 Dec 30. J Immunol. 2010. PMID: 20042577
C17 prevents inflammatory arthritis and associated joint destruction in mice.
Chao C, Joyce-Shaikh B, Grein J, Moshrefi M, Raoufi F, Laface DM, McClanahan TK, Bourne PA, Pierce RH, Gorman DM, Pflanz S. Chao C, et al. Among authors: pierce rh. PLoS One. 2011;6(7):e22256. doi: 10.1371/journal.pone.0022256. Epub 2011 Jul 25. PLoS One. 2011. PMID: 21799806 Free PMC article.
Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease.
Cayatte C, Joyce-Shaikh B, Vega F, Boniface K, Grein J, Murphy E, Blumenschein WM, Chen S, Malinao MC, Basham B, Pierce RH, Bowman EP, McKenzie BS, Elson CO, Faubion WA, Malefyt Rde W, Kastelein RA, Cua D, McClanahan TK, Beaumont M. Cayatte C, et al. Among authors: pierce rh. Clin Transl Gastroenterol. 2012 Feb 16;3(2):e10. doi: 10.1038/ctg.2012.2. Clin Transl Gastroenterol. 2012. PMID: 23238132 Free PMC article.
PD-1 blockade induces responses by inhibiting adaptive immune resistance.
Tumeh PC, Harview CL, Yearley JH, Shintaku IP, Taylor EJ, Robert L, Chmielowski B, Spasic M, Henry G, Ciobanu V, West AN, Carmona M, Kivork C, Seja E, Cherry G, Gutierrez AJ, Grogan TR, Mateus C, Tomasic G, Glaspy JA, Emerson RO, Robins H, Pierce RH, Elashoff DA, Robert C, Ribas A. Tumeh PC, et al. Among authors: pierce rh. Nature. 2014 Nov 27;515(7528):568-71. doi: 10.1038/nature13954. Nature. 2014. PMID: 25428505 Free PMC article. Clinical Trial.
147 results