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Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and transforming growth factor-beta signaling pathways.
Iwanaga R, Wang CA, Micalizzi DS, Harrell JC, Jedlicka P, Sartorius CA, Kabos P, Farabaugh SM, Bradford AP, Ford HL. Iwanaga R, et al. Breast Cancer Res. 2012 Jul 5;14(4):R100. doi: 10.1186/bcr3219. Breast Cancer Res. 2012. PMID: 22765220 Free PMC article.
Ectopic expression of the CDK inhibitor p21Cip1 enhances deregulated E2F activity and increases cancer cell-specific cytotoxic gene expression mediated by the ARF tumor suppressor promoter.
Kurayoshi K, Shiromoto A, Ozono E, Iwanaga R, Bradford AP, Araki K, Ohtani K. Kurayoshi K, et al. Among authors: iwanaga r. Biochem Biophys Res Commun. 2017 Jan 29;483(1):107-114. doi: 10.1016/j.bbrc.2016.12.185. Epub 2016 Dec 29. Biochem Biophys Res Commun. 2017. PMID: 28042030
Deregulated E2F Activity as a Cancer-Cell Specific Therapeutic Tool.
Nakajima R, Zhao L, Zhou Y, Shirasawa M, Uchida A, Murakawa H, Fikriyanti M, Iwanaga R, Bradford AP, Araki K, Warita T, Ohtani K. Nakajima R, et al. Among authors: iwanaga r. Genes (Basel). 2023 Feb 2;14(2):393. doi: 10.3390/genes14020393. Genes (Basel). 2023. PMID: 36833320 Free PMC article. Review.
122 results