Johnstone RW - Search Results

1

Granzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737.

Sutton VR, Sedelies K, Dewson G, Christensen ME, Bird PI, Johnstone RW, Kluck RM, Trapani JA, Waterhouse NJ. Sutton VR, et al. Among authors: johnstone rw. Cell Death Dis. 2012 Jul 5;3(7):e344. doi: 10.1038/cddis.2012.73. Cell Death Dis. 2012. PMID: 22764103 Free PMC article.

2

Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma.

DeYoung KL, Ray ME, Su YA, Anzick SL, Johnstone RW, Trapani JA, Meltzer PS, Trent JM. DeYoung KL, et al. Among authors: johnstone rw. Oncogene. 1997 Jul 24;15(4):453-7. doi: 10.1038/sj.onc.1201206. Oncogene. 1997. PMID: 9242382

3

The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis.

Smyth MJ, Krasovskis E, Sutton VR, Johnstone RW. Smyth MJ, et al. Among authors: johnstone rw. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):7024-9. doi: 10.1073/pnas.95.12.7024. Proc Natl Acad Sci U S A. 1998. PMID: 9618532 Free PMC article.

4

The human interferon-inducible protein, IFI 16, is a repressor of transcription.

Johnstone RW, Kerry JA, Trapani JA. Johnstone RW, et al. J Biol Chem. 1998 Jul 3;273(27):17172-7. doi: 10.1074/jbc.273.27.17172. J Biol Chem. 1998. PMID: 9642285 Free article.

5

Isotypic variants of the interferon-inducible transcriptional repressor IFI 16 arise through differential mRNA splicing.

Johnstone RW, Kershaw MH, Trapani JA. Johnstone RW, et al. Biochemistry. 1998 Aug 25;37(34):11924-31. doi: 10.1021/bi981069a. Biochemistry. 1998. PMID: 9718316

6

The IFN-inducible nucleoprotein IFI 16 is expressed in cells of the monocyte lineage, but is rapidly and markedly down-regulated in other myeloid precursor populations.

Dawson MJ, Elwood NJ, Johnstone RW, Trapani JA. Dawson MJ, et al. Among authors: johnstone rw. J Leukoc Biol. 1998 Oct;64(4):546-54. doi: 10.1002/jlb.64.4.546. J Leukoc Biol. 1998. PMID: 9766636

7

Transcription and growth regulatory functions of the HIN-200 family of proteins.

Johnstone RW, Trapani JA. Johnstone RW, et al. Mol Cell Biol. 1999 Sep;19(9):5833-8. doi: 10.1128/MCB.19.9.5833. Mol Cell Biol. 1999. PMID: 10454530 Free PMC article. Review. No abstract available.

8

Filamin (280-kDa actin-binding protein) is a caspase substrate and is also cleaved directly by the cytotoxic T lymphocyte protease granzyme B during apoptosis.

Browne KA, Johnstone RW, Jans DA, Trapani JA. Browne KA, et al. Among authors: johnstone rw. J Biol Chem. 2000 Dec 15;275(50):39262-6. doi: 10.1074/jbc.C000622200. J Biol Chem. 2000. PMID: 11050075 Free article.

9

Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

Sutton VR, Davis JE, Cancilla M, Johnstone RW, Ruefli AA, Sedelies K, Browne KA, Trapani JA. Sutton VR, et al. Among authors: johnstone rw. J Exp Med. 2000 Nov 20;192(10):1403-14. doi: 10.1084/jem.192.10.1403. J Exp Med. 2000. PMID: 11085743 Free PMC article.

10

Novel properties of the protein kinase CK2-site-regulated nuclear- localization sequence of the interferon-induced nuclear factor IFI 16.

Briggs LJ, Johnstone RW, Elliot RM, Xiao CY, Dawson M, Trapani JA, Jans DA. Briggs LJ, et al. Among authors: johnstone rw. Biochem J. 2001 Jan 1;353(Pt 1):69-77. Biochem J. 2001. PMID: 11115400 Free PMC article.

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