Dennis PA - Search Results

1

Ceramide mediates nanovesicle shedding and cell death in response to phosphatidylinositol ether lipid analogs and perifosine.

Gills JJ, Zhang C, Abu-Asab MS, Castillo SS, Marceau C, LoPiccolo J, Kozikowski AP, Tsokos M, Goldkorn T, Dennis PA. Gills JJ, et al. Among authors: dennis pa. Cell Death Dis. 2012 Jul 5;3(7):e340. doi: 10.1038/cddis.2012.72. Cell Death Dis. 2012. PMID: 22764099 Free PMC article.

2

Variable apoptotic response of NSCLC cells to inhibition of the MEK/ERK pathway by small molecules or dominant negative mutants.

Brognard J, Dennis PA. Brognard J, et al. Among authors: dennis pa. Cell Death Differ. 2002 Sep;9(9):893-904. doi: 10.1038/sj.cdd.4401054. Cell Death Differ. 2002. PMID: 12181740

3

Activation of the PI3K/Akt pathway and chemotherapeutic resistance.

West KA, Castillo SS, Dennis PA. West KA, et al. Among authors: dennis pa. Drug Resist Updat. 2002 Dec;5(6):234-48. doi: 10.1016/s1368-7646(02)00120-6. Drug Resist Updat. 2002. PMID: 12531180 Review.

4

Novel PI analogues selectively block activation of the pro-survival serine/threonine kinase Akt.

Kozikowski AP, Sun H, Brognard J, Dennis PA. Kozikowski AP, et al. Among authors: dennis pa. J Am Chem Soc. 2003 Feb 5;125(5):1144-5. doi: 10.1021/ja0285159. J Am Chem Soc. 2003. PMID: 12553797

5

Immune evasion by murine melanoma mediated through CC chemokine receptor-10.

Murakami T, Cardones AR, Finkelstein SE, Restifo NP, Klaunberg BA, Nestle FO, Castillo SS, Dennis PA, Hwang ST. Murakami T, et al. Among authors: dennis pa. J Exp Med. 2003 Nov 3;198(9):1337-47. doi: 10.1084/jem.20030593. Epub 2003 Oct 27. J Exp Med. 2003. PMID: 14581607 Free PMC article.

6

Tobacco carcinogen-induced cellular transformation increases activation of the phosphatidylinositol 3'-kinase/Akt pathway in vitro and in vivo.

West KA, Linnoila IR, Belinsky SA, Harris CC, Dennis PA. West KA, et al. Among authors: dennis pa. Cancer Res. 2004 Jan 15;64(2):446-51. doi: 10.1158/0008-5472.can-03-3241. Cancer Res. 2004. PMID: 14744754

7

Targeting aberrant signal transduction pathways in lung cancer.

Gills JJ, Granville CA, Dennis PA. Gills JJ, et al. Among authors: dennis pa. Cancer Biol Ther. 2004 Feb;3(2):147-55. doi: 10.4161/cbt.3.2.612. Epub 2004 Feb 1. Cancer Biol Ther. 2004. PMID: 14764993 Free article. Review.

8

Preferential inhibition of Akt and killing of Akt-dependent cancer cells by rationally designed phosphatidylinositol ether lipid analogues.

Castillo SS, Brognard J, Petukhov PA, Zhang C, Tsurutani J, Granville CA, Li M, Jung M, West KA, Gills JG, Kozikowski AP, Dennis PA. Castillo SS, et al. Among authors: dennis pa. Cancer Res. 2004 Apr 15;64(8):2782-92. doi: 10.1158/0008-5472.can-03-1530. Cancer Res. 2004. PMID: 15087394

9

The development of phosphatidylinositol ether lipid analogues as inhibitors of the serine/threonine kinase, Akt.

Gills JJ, Dennis PA. Gills JJ, et al. Among authors: dennis pa. Expert Opin Investig Drugs. 2004 Jul;13(7):787-97. doi: 10.1517/13543784.13.7.787. Expert Opin Investig Drugs. 2004. PMID: 15212619 Review.

10

Genetic and pharmacologic identification of Akt as a mediator of brain-derived neurotrophic factor/TrkB rescue of neuroblastoma cells from chemotherapy-induced cell death.

Li Z, Jaboin J, Dennis PA, Thiele CJ. Li Z, et al. Among authors: dennis pa. Cancer Res. 2005 Mar 15;65(6):2070-5. doi: 10.1158/0008-5472.CAN-04-3606. Cancer Res. 2005. PMID: 15781614

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