Spiegel DA - Search Results

1

Antibody-recruiting molecules: an emerging paradigm for engaging immune function in treating human disease.

McEnaney PJ, Parker CG, Zhang AX, Spiegel DA. McEnaney PJ, et al. Among authors: spiegel da. ACS Chem Biol. 2012 Jul 20;7(7):1139-51. doi: 10.1021/cb300119g. Epub 2012 Jul 3. ACS Chem Biol. 2012. PMID: 22758917 Free PMC article. Review.

2

An antibody-recruiting small molecule that targets HIV gp120.

Parker CG, Domaoal RA, Anderson KS, Spiegel DA. Parker CG, et al. Among authors: spiegel da. J Am Chem Soc. 2009 Nov 18;131(45):16392-4. doi: 10.1021/ja9057647. J Am Chem Soc. 2009. PMID: 19839582 Free PMC article.

3

Chemical control over immune recognition: a class of antibody-recruiting small molecules that target prostate cancer.

Murelli RP, Zhang AX, Michel J, Jorgensen WL, Spiegel DA. Murelli RP, et al. Among authors: spiegel da. J Am Chem Soc. 2009 Dec 2;131(47):17090-2. doi: 10.1021/ja906844e. J Am Chem Soc. 2009. PMID: 19888723 Free PMC article.

4

A remote arene-binding site on prostate specific membrane antigen revealed by antibody-recruiting small molecules.

Zhang AX, Murelli RP, Barinka C, Michel J, Cocleaza A, Jorgensen WL, Lubkowski J, Spiegel DA. Zhang AX, et al. Among authors: spiegel da. J Am Chem Soc. 2010 Sep 15;132(36):12711-6. doi: 10.1021/ja104591m. J Am Chem Soc. 2010. PMID: 20726553 Free PMC article.

5

A biosynthetic strategy for re-engineering the Staphylococcus aureus cell wall with non-native small molecules.

Nelson JW, Chamessian AG, McEnaney PJ, Murelli RP, Kazmierczak BI, Spiegel DA. Nelson JW, et al. Among authors: spiegel da. ACS Chem Biol. 2010 Dec 17;5(12):1147-55. doi: 10.1021/cb100195d. Epub 2010 Oct 5. ACS Chem Biol. 2010. PMID: 20923200 Free PMC article.

6

Grand challenge commentary: Synthetic immunology to engineer human immunity.

Spiegel DA. Spiegel DA. Nat Chem Biol. 2010 Dec;6(12):871-2. doi: 10.1038/nchembio.477. Nat Chem Biol. 2010. PMID: 21079593

7

A chemically induced vaccine strategy for prostate cancer.

Dubrovska A, Kim C, Elliott J, Shen W, Kuo TH, Koo DI, Li C, Tuntland T, Chang J, Groessl T, Wu X, Gorney V, Ramirez-Montagut T, Spiegel DA, Cho CY, Schultz PG. Dubrovska A, et al. Among authors: spiegel da. ACS Chem Biol. 2011 Nov 18;6(11):1223-31. doi: 10.1021/cb200222s. Epub 2011 Sep 21. ACS Chem Biol. 2011. PMID: 21936526

8

Reprogramming urokinase into an antibody-recruiting anticancer agent.

Jakobsche CE, McEnaney PJ, Zhang AX, Spiegel DA. Jakobsche CE, et al. Among authors: spiegel da. ACS Chem Biol. 2012 Feb 17;7(2):316-21. doi: 10.1021/cb200374e. Epub 2011 Nov 18. ACS Chem Biol. 2012. PMID: 22098560 Free PMC article.

9

Exploring binding and effector functions of natural human antibodies using synthetic immunomodulators.

Jakobsche CE, Parker CG, Tao RN, Kolesnikova MD, Douglass EF Jr, Spiegel DA. Jakobsche CE, et al. Among authors: spiegel da. ACS Chem Biol. 2013 Nov 15;8(11):2404-11. doi: 10.1021/cb4004942. Epub 2013 Sep 20. ACS Chem Biol. 2013. PMID: 24053626 Free PMC article.

10

Illuminating HIV gp120-Ligand Recognition through Computationally-Driven Optimization of Antibody-Recruiting Molecules.

Parker CG, Dahlgren MK, Tao RN, Li DT, Douglass EF Jr, Shoda T, Jawanda N, Spasov KA, Lee S, Zhou N, Domaoal RA, Sutton RE, Anderson KS, Jorgensen WL, Krystal M, Spiegel DA. Parker CG, et al. Among authors: spiegel da. Chem Sci. 2014 Jun 1;5(6):2311-2317. doi: 10.1039/C4SC00484A. Chem Sci. 2014. PMID: 25379167 Free PMC article.

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