Wirth T - Search Results

1

Requirement of NEMO/IKKγ for effective expansion of KRAS-induced precancerous lesions in the pancreas.

Maier HJ, Wagner M, Schips TG, Salem HH, Baumann B, Wirth T. Maier HJ, et al. Among authors: wirth t. Oncogene. 2013 May 23;32(21):2690-5. doi: 10.1038/onc.2012.272. Epub 2012 Jul 2. Oncogene. 2013. PMID: 22751123

2

Cellular immune reaction in the pancreas is induced by constitutively active IkappaB kinase-2.

Aleksic T, Baumann B, Wagner M, Adler G, Wirth T, Weber CK. Aleksic T, et al. Among authors: wirth t. Gut. 2007 Feb;56(2):227-36. doi: 10.1136/gut.2005.084665. Epub 2006 Jul 26. Gut. 2007. PMID: 16870717 Free PMC article.

3

Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo.

Baumann B, Wagner M, Aleksic T, von Wichert G, Weber CK, Adler G, Wirth T. Baumann B, et al. Among authors: wirth t. J Clin Invest. 2007 Jun;117(6):1502-13. doi: 10.1172/JCI30876. Epub 2007 May 24. J Clin Invest. 2007. PMID: 17525799 Free PMC article.

4

NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells.

Maier HJ, Schmidt-Strassburger U, Huber MA, Wiedemann EM, Beug H, Wirth T. Maier HJ, et al. Among authors: wirth t. Cancer Lett. 2010 Sep 28;295(2):214-28. doi: 10.1016/j.canlet.2010.03.003. Epub 2010 Mar 29. Cancer Lett. 2010. PMID: 20350779

5

FoxO3 induces reversible cardiac atrophy and autophagy in a transgenic mouse model.

Schips TG, Wietelmann A, Höhn K, Schimanski S, Walther P, Braun T, Wirth T, Maier HJ. Schips TG, et al. Among authors: wirth t. Cardiovasc Res. 2011 Sep 1;91(4):587-97. doi: 10.1093/cvr/cvr144. Epub 2011 May 30. Cardiovasc Res. 2011. PMID: 21628326

6

Cardiomyocyte-specific IκB kinase (IKK)/NF-κB activation induces reversible inflammatory cardiomyopathy and heart failure.

Maier HJ, Schips TG, Wietelmann A, Krüger M, Brunner C, Sauter M, Klingel K, Böttger T, Braun T, Wirth T. Maier HJ, et al. Among authors: wirth t. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11794-9. doi: 10.1073/pnas.1116584109. Epub 2012 Jul 2. Proc Natl Acad Sci U S A. 2012. PMID: 22753500 Free PMC article.

7

Long-term IKK2/NF-κB signaling in pancreatic β-cells induces immune-mediated diabetes.

Salem HH, Trojanowski B, Fiedler K, Maier HJ, Schirmbeck R, Wagner M, Boehm BO, Wirth T, Baumann B. Salem HH, et al. Among authors: wirth t. Diabetes. 2014 Mar;63(3):960-75. doi: 10.2337/db13-1037. Epub 2013 Dec 2. Diabetes. 2014. PMID: 24296718

8

Epithelial NEMO/IKKγ limits fibrosis and promotes regeneration during pancreatitis.

Chan LK, Gerstenlauer M, Konukiewitz B, Steiger K, Weichert W, Wirth T, Maier HJ. Chan LK, et al. Among authors: wirth t. Gut. 2017 Nov;66(11):1995-2007. doi: 10.1136/gutjnl-2015-311028. Epub 2016 Jul 27. Gut. 2017. PMID: 27464707

9

Block of NF-kB signaling accelerates MYC-driven hepatocellular carcinogenesis and modifies the tumor phenotype towards combined hepatocellular cholangiocarcinoma.

He J, Gerstenlauer M, Chan LK, Leithäuser F, Yeh MM, Wirth T, Maier HJ. He J, et al. Among authors: wirth t. Cancer Lett. 2019 Aug 28;458:113-122. doi: 10.1016/j.canlet.2019.05.023. Epub 2019 May 22. Cancer Lett. 2019. PMID: 31128214 Free article.

10

Elevated β-cell stress levels promote severe diabetes development in mice with MODY4.

Trojanowski BM, Salem HH, Neubauer H, Simon E, Wagner M, Dorajoo R, Boehm BO, Labriola L, Wirth T, Baumann B. Trojanowski BM, et al. Among authors: wirth t. J Endocrinol. 2020 Feb;244(2):323-337. doi: 10.1530/JOE-19-0208. J Endocrinol. 2020. PMID: 31682591 Free PMC article.

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