Lehner PJ - Search Results

1

Fluorescence-based phenotypic selection allows forward genetic screens in haploid human cells.

Duncan LM, Timms RT, Zavodszky E, Cano F, Dougan G, Randow F, Lehner PJ. Duncan LM, et al. Among authors: lehner pj. PLoS One. 2012;7(6):e39651. doi: 10.1371/journal.pone.0039651. Epub 2012 Jun 22. PLoS One. 2012. PMID: 22745803 Free PMC article.

2

Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation.

Hewitt EW, Duncan L, Mufti D, Baker J, Stevenson PG, Lehner PJ. Hewitt EW, et al. Among authors: lehner pj. EMBO J. 2002 May 15;21(10):2418-29. doi: 10.1093/emboj/21.10.2418. EMBO J. 2002. PMID: 12006494 Free PMC article.

3

Solution structure of the Kaposi's sarcoma-associated herpesvirus K3 N-terminal domain reveals a Novel E2-binding C4HC3-type RING domain.

Dodd RB, Allen MD, Brown SE, Sanderson CM, Duncan LM, Lehner PJ, Bycroft M, Read RJ. Dodd RB, et al. Among authors: lehner pj. J Biol Chem. 2004 Dec 17;279(51):53840-7. doi: 10.1074/jbc.M409662200. Epub 2004 Sep 30. J Biol Chem. 2004. PMID: 15465811 Free article.

4

Downregulation of cell surface receptors by the K3 family of viral and cellular ubiquitin E3 ligases.

Lehner PJ, Hoer S, Dodd R, Duncan LM. Lehner PJ, et al. Immunol Rev. 2005 Oct;207:112-25. doi: 10.1111/j.0105-2896.2005.00314.x. Immunol Rev. 2005. PMID: 16181331 Review.

5

Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules.

Duncan LM, Piper S, Dodd RB, Saville MK, Sanderson CM, Luzio JP, Lehner PJ. Duncan LM, et al. Among authors: lehner pj. EMBO J. 2006 Apr 19;25(8):1635-45. doi: 10.1038/sj.emboj.7601056. Epub 2006 Apr 6. EMBO J. 2006. PMID: 16601694 Free PMC article.

6

Viral avoidance and exploitation of the ubiquitin system.

Randow F, Lehner PJ. Randow F, et al. Among authors: lehner pj. Nat Cell Biol. 2009 May;11(5):527-34. doi: 10.1038/ncb0509-527. Nat Cell Biol. 2009. PMID: 19404332 Review.

7

Stabilization of an E3 ligase-E2-ubiquitin complex increases cell surface MHC class I expression.

Duncan LM, Nathan JA, Lehner PJ. Duncan LM, et al. Among authors: lehner pj. J Immunol. 2010 Jun 15;184(12):6978-85. doi: 10.4049/jimmunol.0904154. Epub 2010 May 12. J Immunol. 2010. PMID: 20483773 Free PMC article.

8

Comparative analysis of techniques to purify plasma membrane proteins.

Weekes MP, Antrobus R, Lill JR, Duncan LM, Hör S, Lehner PJ. Weekes MP, et al. Among authors: lehner pj. J Biomol Tech. 2010 Sep;21(3):108-15. J Biomol Tech. 2010. PMID: 20808639 Free PMC article.

9

RNA-binding E3 ubiquitin ligases: novel players in nucleic acid regulation.

Cano F, Miranda-Saavedra D, Lehner PJ. Cano F, et al. Among authors: lehner pj. Biochem Soc Trans. 2010 Dec;38(6):1621-6. doi: 10.1042/BST0381621. Biochem Soc Trans. 2010. PMID: 21118137

10

HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation.

Burr ML, Cano F, Svobodova S, Boyle LH, Boname JM, Lehner PJ. Burr ML, et al. Among authors: lehner pj. Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):2034-9. doi: 10.1073/pnas.1016229108. Epub 2011 Jan 18. Proc Natl Acad Sci U S A. 2011. PMID: 21245296 Free PMC article.

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