Duncan LM - Search Results

1

Fluorescence-based phenotypic selection allows forward genetic screens in haploid human cells.

Duncan LM, Timms RT, Zavodszky E, Cano F, Dougan G, Randow F, Lehner PJ. Duncan LM, et al. PLoS One. 2012;7(6):e39651. doi: 10.1371/journal.pone.0039651. Epub 2012 Jun 22. PLoS One. 2012. PMID: 22745803 Free PMC article.

2

Haploid genetic screens identify an essential role for PLP2 in the downregulation of novel plasma membrane targets by viral E3 ubiquitin ligases.

Timms RT, Duncan LM, Tchasovnikarova IA, Antrobus R, Smith DL, Dougan G, Weekes MP, Lehner PJ. Timms RT, et al. Among authors: duncan lm. PLoS Pathog. 2013;9(11):e1003772. doi: 10.1371/journal.ppat.1003772. Epub 2013 Nov 21. PLoS Pathog. 2013. PMID: 24278019 Free PMC article.

3

Stabilization of an E3 ligase-E2-ubiquitin complex increases cell surface MHC class I expression.

Duncan LM, Nathan JA, Lehner PJ. Duncan LM, et al. J Immunol. 2010 Jun 15;184(12):6978-85. doi: 10.4049/jimmunol.0904154. Epub 2010 May 12. J Immunol. 2010. PMID: 20483773 Free PMC article.

4

The RNA-binding E3 ubiquitin ligase MEX-3C links ubiquitination with MHC-I mRNA degradation.

Cano F, Bye H, Duncan LM, Buchet-Poyau K, Billaud M, Wills MR, Lehner PJ. Cano F, et al. Among authors: duncan lm. EMBO J. 2012 Aug 29;31(17):3596-606. doi: 10.1038/emboj.2012.218. Epub 2012 Aug 3. EMBO J. 2012. PMID: 22863774 Free PMC article.

5

Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation.

Hewitt EW, Duncan L, Mufti D, Baker J, Stevenson PG, Lehner PJ. Hewitt EW, et al. EMBO J. 2002 May 15;21(10):2418-29. doi: 10.1093/emboj/21.10.2418. EMBO J. 2002. PMID: 12006494 Free PMC article.

6

Downregulation of cell surface receptors by the K3 family of viral and cellular ubiquitin E3 ligases.

Lehner PJ, Hoer S, Dodd R, Duncan LM. Lehner PJ, et al. Among authors: duncan lm. Immunol Rev. 2005 Oct;207:112-25. doi: 10.1111/j.0105-2896.2005.00314.x. Immunol Rev. 2005. PMID: 16181331 Review.

7

Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway.

Boyle LH, Hermann C, Boname JM, Porter KM, Patel PA, Burr ML, Duncan LM, Harbour ME, Rhodes DA, Skjødt K, Lehner PJ, Trowsdale J. Boyle LH, et al. Among authors: duncan lm. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3465-70. doi: 10.1073/pnas.1222342110. Epub 2013 Feb 11. Proc Natl Acad Sci U S A. 2013. PMID: 23401559 Free PMC article.

8

Solution structure of the Kaposi's sarcoma-associated herpesvirus K3 N-terminal domain reveals a Novel E2-binding C4HC3-type RING domain.

Dodd RB, Allen MD, Brown SE, Sanderson CM, Duncan LM, Lehner PJ, Bycroft M, Read RJ. Dodd RB, et al. Among authors: duncan lm. J Biol Chem. 2004 Dec 17;279(51):53840-7. doi: 10.1074/jbc.M409662200. Epub 2004 Sep 30. J Biol Chem. 2004. PMID: 15465811 Free article.

9

Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules.

Duncan LM, Piper S, Dodd RB, Saville MK, Sanderson CM, Luzio JP, Lehner PJ. Duncan LM, et al. EMBO J. 2006 Apr 19;25(8):1635-45. doi: 10.1038/sj.emboj.7601056. Epub 2006 Apr 6. EMBO J. 2006. PMID: 16601694 Free PMC article.

10

Comparative analysis of techniques to purify plasma membrane proteins.

Weekes MP, Antrobus R, Lill JR, Duncan LM, Hör S, Lehner PJ. Weekes MP, et al. Among authors: duncan lm. J Biomol Tech. 2010 Sep;21(3):108-15. J Biomol Tech. 2010. PMID: 20808639 Free PMC article.

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