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The efficacy and tolerability of artemisinin-piperaquine (Artequick®) versus artesunate-amodiaquine (Coarsucam™) for the treatment of uncomplicated Plasmodium falciparum malaria in south-central Vietnam.
Thanh NX, Trung TN, Phong NC, Quang HH, Dai B, Shanks GD, Chavchich M, Edstein MD. Thanh NX, et al. Among authors: chavchich m. Malar J. 2012 Jun 28;11:217. doi: 10.1186/1475-2875-11-217. Malar J. 2012. PMID: 22741618 Free PMC article. Clinical Trial.
Open label randomized comparison of dihydroartemisinin-piperaquine and artesunate-amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in central Vietnam.
Thanh NX, Trung TN, Phong NC, Thien NX, Dai B, Shanks GD, Chavchich M, Edstein MD. Thanh NX, et al. Among authors: chavchich m. Trop Med Int Health. 2009 May;14(5):504-11. doi: 10.1111/j.1365-3156.2009.02269.x. Epub 2009 Mar 19. Trop Med Int Health. 2009. PMID: 19320869 Free article. Clinical Trial.
Pharmacokinetics and ex vivo pharmacodynamic antimalarial activity of dihydroartemisinin-piperaquine in patients with uncomplicated falciparum malaria in Vietnam.
Nguyen DV, Nguyen QP, Nguyen ND, Le TT, Nguyen TD, Dinh DN, Nguyen TX, Bui D, Chavchich M, Edstein MD. Nguyen DV, et al. Among authors: chavchich m. Antimicrob Agents Chemother. 2009 Aug;53(8):3534-7. doi: 10.1128/AAC.01717-08. Epub 2009 Jun 15. Antimicrob Agents Chemother. 2009. PMID: 19528277 Free PMC article. Clinical Trial.
JPC-2997, a new aminomethylphenol with high in vitro and in vivo antimalarial activities against blood stages of Plasmodium.
Birrell GW, Chavchich M, Ager AL, Shieh HM, Heffernan GD, Zhao W, Krasucki PE, Saionz KW, Terpinski J, Schiehser GA, Jacobus LR, Shanks GD, Jacobus DP, Edstein MD. Birrell GW, et al. Among authors: chavchich m. Antimicrob Agents Chemother. 2015 Jan;59(1):170-7. doi: 10.1128/AAC.03762-14. Epub 2014 Oct 20. Antimicrob Agents Chemother. 2015. PMID: 25331702 Free PMC article.
Aza-acyclic nucleoside phosphonates containing a second phosphonate group as inhibitors of the human, Plasmodium falciparum and vivax 6-oxopurine phosphoribosyltransferases and their prodrugs as antimalarial agents.
Keough DT, Hocková D, Janeba Z, Wang TH, Naesens L, Edstein MD, Chavchich M, Guddat LW. Keough DT, et al. Among authors: chavchich m. J Med Chem. 2015 Jan 22;58(2):827-46. doi: 10.1021/jm501416t. Epub 2014 Dec 24. J Med Chem. 2015. PMID: 25494538
Development of cultured Plasmodium falciparum blood-stage malaria cell banks for early phase in vivo clinical trial assessment of anti-malaria drugs and vaccines.
Stanisic DI, Liu XQ, De SL, Batzloff MR, Forbes T, Davis CB, Sekuloski S, Chavchich M, Chung W, Trenholme K, McCarthy JS, Li T, Sim BK, Hoffman SL, Good MF. Stanisic DI, et al. Among authors: chavchich m. Malar J. 2015 Apr 7;14:143. doi: 10.1186/s12936-015-0663-x. Malar J. 2015. PMID: 25890156 Free PMC article.
48 results