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CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice.
Mancuso R, Fryatt G, Cleal M, Obst J, Pipi E, Monzón-Sandoval J, Ribe E, Winchester L, Webber C, Nevado A, Jacobs T, Austin N, Theunis C, Grauwen K, Daniela Ruiz E, Mudher A, Vicente-Rodriguez M, Parker CA, Simmons C, Cash D, Richardson J; NIMA Consortium; Jones DNC, Lovestone S, Gómez-Nicola D, Perry VH. Mancuso R, et al. Brain. 2019 Oct 1;142(10):3243-3264. doi: 10.1093/brain/awz241. Brain. 2019. PMID: 31504240 Free PMC article.
Transcriptional profiling of macaque microglia reveals an evolutionary preserved gene expression program.
Dubbelaar ML, Misrielal C, Bajramovic JJ, Burm SM, Zuiderwijk-Sick EA, Brouwer N, Grit C, Kooistra SM, Shinjo SMO, Marie SKN, Boddeke HWGM, Eggen BJL. Dubbelaar ML, et al. Among authors: boddeke hwgm. Brain Behav Immun Health. 2021 May 7;15:100265. doi: 10.1016/j.bbih.2021.100265. eCollection 2021 Aug. Brain Behav Immun Health. 2021. PMID: 34589771 Free PMC article.
Inflammatory biomarkers in Alzheimer's disease plasma.
Morgan AR, Touchard S, Leckey C, O'Hagan C, Nevado-Holgado AJ; NIMA Consortium; Barkhof F, Bertram L, Blin O, Bos I, Dobricic V, Engelborghs S, Frisoni G, Frölich L, Gabel S, Johannsen P, Kettunen P, Kłoszewska I, Legido-Quigley C, Lleó A, Martinez-Lage P, Mecocci P, Meersmans K, Molinuevo JL, Peyratout G, Popp J, Richardson J, Sala I, Scheltens P, Streffer J, Soininen H, Tainta-Cuezva M, Teunissen C, Tsolaki M, Vandenberghe R, Visser PJ, Vos S, Wahlund LO, Wallin A, Westwood S, Zetterberg H, Lovestone S, Morgan BP; Annex: NIMA–Wellcome Trust Consortium for Neuroimmunology of Mood Disorders and Alzheimer's Disease. Morgan AR, et al. Alzheimers Dement. 2019 Jun;15(6):776-787. doi: 10.1016/j.jalz.2019.03.007. Epub 2019 Apr 30. Alzheimers Dement. 2019. PMID: 31047856 Free PMC article.
Microglia in Physiology and Disease.
Wolf SA, Boddeke HW, Kettenmann H. Wolf SA, et al. Among authors: boddeke hw. Annu Rev Physiol. 2017 Feb 10;79:619-643. doi: 10.1146/annurev-physiol-022516-034406. Epub 2016 Dec 7. Annu Rev Physiol. 2017. PMID: 27959620 Review.
Aging, microglia and cytoskeletal regulation are key factors in the pathological evolution of the APP23 mouse model for Alzheimer's disease.
Janssen L, Dubbelaar ML, Holtman IR, de Boer-Bergsma J, Eggen BJ, Boddeke HW, De Deyn PP, Van Dam D. Janssen L, et al. Among authors: boddeke hw. Biochim Biophys Acta Mol Basis Dis. 2017 Feb;1863(2):395-405. doi: 10.1016/j.bbadis.2016.11.014. Epub 2016 Nov 10. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 27838490 Free article.
135 results