Vugmeyster Y - Search Results

1

Pharmacokinetic, biodistribution, and biophysical profiles of TNF nanobodies conjugated to linear or branched poly(ethylene glycol).

Vugmeyster Y, Entrican CA, Joyce AP, Lawrence-Henderson RF, Leary BA, Mahoney CS, Patel HK, Raso SW, Olland SH, Hegen M, Xu X. Vugmeyster Y, et al. Bioconjug Chem. 2012 Jul 18;23(7):1452-62. doi: 10.1021/bc300066a. Epub 2012 Jun 25. Bioconjug Chem. 2012. PMID: 22731748

2

Absorption, distribution, metabolism, and excretion (ADME) studies of biotherapeutics for autoimmune and inflammatory conditions.

Vugmeyster Y, Harrold J, Xu X. Vugmeyster Y, et al. AAPS J. 2012 Dec;14(4):714-27. doi: 10.1208/s12248-012-9385-y. Epub 2012 Jul 14. AAPS J. 2012. PMID: 22798020 Free PMC article. Review.

3

Biodistribution of [125I]-labeled therapeutic proteins: application in protein drug development beyond oncology.

Vugmeyster Y, DeFranco D, Szklut P, Wang Q, Xu X. Vugmeyster Y, et al. J Pharm Sci. 2010 Feb;99(2):1028-45. doi: 10.1002/jps.21855. J Pharm Sci. 2010. PMID: 19569059

4

Preclinical pharmacokinetics, interspecies scaling, and tissue distribution of humanized monoclonal anti-IL-13 antibodies with different IL-13 neutralization mechanisms.

Vugmeyster Y, Szklut P, Tchistiakova L, Abraham W, Kasaian M, Xu X. Vugmeyster Y, et al. Int Immunopharmacol. 2008 Mar;8(3):477-83. doi: 10.1016/j.intimp.2007.12.004. Epub 2008 Jan 11. Int Immunopharmacol. 2008. PMID: 18279802

5

Pharmacokinetics and lung distribution of a humanized anti-RAGE antibody in wild-type and RAGE-/- mice.

Vugmeyster Y, DeFranco D, Pittman DD, Xu X. Vugmeyster Y, et al. MAbs. 2010 Sep-Oct;2(5):571-5. doi: 10.4161/mabs.2.5.13089. Epub 2010 Sep 1. MAbs. 2010. PMID: 20978371 Free PMC article.

6

Complex pharmacokinetics of a humanized antibody against human amyloid beta peptide, anti-abeta Ab2, in nonclinical species.

Vugmeyster Y, Szklut P, Wensel D, Ross J, Xu X, Awwad M, Gill D, Tchistiakov L, Warner G. Vugmeyster Y, et al. Pharm Res. 2011 Jul;28(7):1696-706. doi: 10.1007/s11095-011-0405-x. Epub 2011 Mar 18. Pharm Res. 2011. PMID: 21424161

7

Pharmacokinetics and toxicology of therapeutic proteins: Advances and challenges.

Vugmeyster Y, Xu X, Theil FP, Khawli LA, Leach MW. Vugmeyster Y, et al. World J Biol Chem. 2012 Apr 26;3(4):73-92. doi: 10.4331/wjbc.v3.i4.73. World J Biol Chem. 2012. PMID: 22558487 Free PMC article.

8

Pharmacokinetic and pharmacodynamic modeling of a humanized anti-IL-13 antibody in naive and Ascaris-challenged cynomolgus monkeys.

Vugmeyster Y, Tian X, Szklut P, Kasaian M, Xu X. Vugmeyster Y, et al. Pharm Res. 2009 Feb;26(2):306-15. doi: 10.1007/s11095-008-9739-4. Epub 2008 Oct 31. Pharm Res. 2009. PMID: 18975059

9

Disposition of human recombinant lubricin in naive rats and in a rat model of post-traumatic arthritis after intra-articular or intravenous administration.

Vugmeyster Y, Wang Q, Xu X, Harrold J, Daugusta D, Li J, Zollner R, Flannery CR, Rivera-Bermúdez MA. Vugmeyster Y, et al. AAPS J. 2012 Mar;14(1):97-104. doi: 10.1208/s12248-011-9315-4. Epub 2012 Jan 7. AAPS J. 2012. PMID: 22228117 Free PMC article.

10

Challenges and opportunities in absorption, distribution, metabolism, and excretion studies of therapeutic biologics.

Xu X, Vugmeyster Y. Xu X, et al. Among authors: vugmeyster y. AAPS J. 2012 Dec;14(4):781-91. doi: 10.1208/s12248-012-9388-8. Epub 2012 Aug 4. AAPS J. 2012. PMID: 22864668 Free PMC article. Review.

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