Cai HY - Search Results

1

The essential role for aromatic cluster in the β3 adrenergic receptor.

Cai HY, Xu ZJ, Tang J, Sun Y, Chen KX, Wang HY, Zhu WL. Cai HY, et al. Acta Pharmacol Sin. 2012 Aug;33(8):1062-8. doi: 10.1038/aps.2012.55. Epub 2012 Jun 25. Acta Pharmacol Sin. 2012. PMID: 22728712 Free PMC article.

2

Discovery of highly selective inhibitors of human fatty acid binding protein 4 (FABP4) by virtual screening.

Cai H, Yan G, Zhang X, Gorbenko O, Wang H, Zhu W. Cai H, et al. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3675-9. doi: 10.1016/j.bmcl.2010.04.095. Epub 2010 Apr 24. Bioorg Med Chem Lett. 2010. PMID: 20471252

3

Classification of 5-HT(1A) receptor agonists and antagonists using GA-SVM method.

Zhu XL, Cai HY, Xu ZJ, Wang Y, Wang HY, Zhang A, Zhu WL. Zhu XL, et al. Among authors: cai hy. Acta Pharmacol Sin. 2011 Nov;32(11):1424-30. doi: 10.1038/aps.2011.112. Epub 2011 Oct 3. Acta Pharmacol Sin. 2011. PMID: 21963891 Free PMC article.

4

Benzbromarone, an old uricosuric drug, inhibits human fatty acid binding protein 4 in vitro and lowers the blood glucose level in db/db mice.

Cai HY, Wang T, Zhao JC, Sun P, Yan GR, Ding HP, Li YX, Wang HY, Zhu WL, Chen KX. Cai HY, et al. Acta Pharmacol Sin. 2013 Nov;34(11):1397-402. doi: 10.1038/aps.2013.97. Epub 2013 Sep 30. Acta Pharmacol Sin. 2013. PMID: 24077632 Free PMC article.

5

Novel fatty acid binding protein 4 (FABP4) inhibitors: virtual screening, synthesis and crystal structure determination.

Cai H, Liu Q, Gao D, Wang T, Chen T, Yan G, Chen K, Xu Y, Wang H, Li Y, Zhu W. Cai H, et al. Eur J Med Chem. 2015 Jan 27;90:241-50. doi: 10.1016/j.ejmech.2014.11.020. Epub 2014 Nov 11. Eur J Med Chem. 2015. PMID: 25461324

6

Combined Virtual Screening and Substructure Search for Discovery of Novel FABP4 Inhibitors.

Cai H, Wang T, Yang Z, Xu Z, Wang G, Wang HY, Zhu W, Chen K. Cai H, et al. J Chem Inf Model. 2017 Sep 25;57(9):2329-2335. doi: 10.1021/acs.jcim.7b00364. Epub 2017 Aug 29. J Chem Inf Model. 2017. PMID: 28810126

7

From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4.

Gao DD, Dou HX, Su HX, Zhang MM, Wang T, Liu QF, Cai HY, Ding HP, Yang Z, Zhu WL, Xu YC, Wang HY, Li YX. Gao DD, et al. Among authors: cai hy. Eur J Med Chem. 2018 Jun 25;154:44-59. doi: 10.1016/j.ejmech.2018.05.007. Epub 2018 May 9. Eur J Med Chem. 2018. PMID: 29775936

8

Corrigendum to "From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4" [Ejmech 154 (2018) 44-59].

Gao DD, Dou HX, Su HX, Zhang MM, Wang T, Liu QF, Cai HY, Ding HP, Yang Z, Zhu WL, Xu YC, Wang HY, Li YX. Gao DD, et al. Among authors: cai hy. Eur J Med Chem. 2019 May 15;170:235-236. doi: 10.1016/j.ejmech.2019.03.016. Epub 2019 Mar 21. Eur J Med Chem. 2019. PMID: 30904781 No abstract available.

9

Discovery of Novel SIRT1/2 Inhibitors with Effective Cytotoxicity against Human Leukemia Cells.

Cai H, Wang Y, Zhang J, Wei Z, Yan T, Feng C, Xu Z, Zhou A, Wu Y. Cai H, et al. J Chem Inf Model. 2023 Aug 14;63(15):4780-4790. doi: 10.1021/acs.jcim.3c00556. Epub 2023 Jul 24. J Chem Inf Model. 2023. PMID: 37486605

10

Molecular mechanism by which RRM2-inhibitor (cholagogue osalmid) plus bafilomycin A1 cause autophagic cell death in multiple myeloma.

Guo S, Xu Z, Feng Q, Zhang H, Yu D, Li B, Hu K, Gao X, Zhang Q, Yi H, Wu X, Song D, Zhu H, Cai H, Peng Y, Zhu W, Shi J. Guo S, et al. Arch Biochem Biophys. 2023 Oct 1;747:109771. doi: 10.1016/j.abb.2023.109771. Epub 2023 Sep 28. Arch Biochem Biophys. 2023. PMID: 37776936

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