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GR-independent down-modulation on GM-CSF bone marrow-derived dendritic cells by the selective glucocorticoid receptor modulator Compound A.
Barcala Tabarrozzi AE, Andreone L, Deckers J, Castro CN, Gimeno ML, Ariolfo L, Berguer PM, Antunica-Noguerol M, Liberman AC, Vettorazzi S, Tuckermann JP, De Bosscher K, Perone MJ. Barcala Tabarrozzi AE, et al. Among authors: de bosscher k. Sci Rep. 2016 Nov 18;6:36646. doi: 10.1038/srep36646. Sci Rep. 2016. PMID: 27857212 Free PMC article.
Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice.
Ballegeer M, Van Looveren K, Timmermans S, Eggermont M, Vandevyver S, Thery F, Dendoncker K, Souffriau J, Vandewalle J, Van Wyngene L, De Rycke R, Takahashi N, Vandenabeele P, Tuckermann J, Reichardt HM, Impens F, Beyaert R, De Bosscher K, Vandenbroucke RE, Libert C. Ballegeer M, et al. Among authors: de rycke r, de bosscher k. J Clin Invest. 2018 Aug 1;128(8):3265-3279. doi: 10.1172/JCI96636. Epub 2018 Jun 25. J Clin Invest. 2018. PMID: 29746256 Free PMC article.
Selective Glucocorticoid Receptor modulators.
De Bosscher K. De Bosscher K. J Steroid Biochem Mol Biol. 2010 May 31;120(2-3):96-104. doi: 10.1016/j.jsbmb.2010.02.027. Epub 2010 Mar 4. J Steroid Biochem Mol Biol. 2010. PMID: 20206690 Review.
Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation.
Beck IM, Drebert ZJ, Hoya-Arias R, Bahar AA, Devos M, Clarisse D, Desmet S, Bougarne N, Ruttens B, Gossye V, Denecker G, Lievens S, Bracke M, Tavernier J, Declercq W, Gevaert K, Vanden Berghe W, Haegeman G, De Bosscher K. Beck IM, et al. Among authors: de bosscher k. PLoS One. 2013 Jul 30;8(7):e69115. doi: 10.1371/journal.pone.0069115. Print 2013. PLoS One. 2013. PMID: 23935933 Free PMC article.
Differential cytokine profiles upon comparing selective versus classic glucocorticoid receptor modulation in human peripheral blood mononuclear cells and inferior turbinate tissue.
Beck IM, Van Crombruggen K, Holtappels G, Daubeuf F, Frossard N, Bachert C, De Bosscher K. Beck IM, et al. Among authors: de bosscher k. PLoS One. 2015 Apr 13;10(4):e0123068. doi: 10.1371/journal.pone.0123068. eCollection 2015. PLoS One. 2015. PMID: 25875480 Free PMC article.
135 results