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259 results

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Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.
Aljayyoussi G, Tyrer HE, Ford L, Sjoberg H, Pionnier N, Waterhouse D, Davies J, Gamble J, Metuge H, Cook DAN, Steven A, Sharma R, Guimaraes AF, Clare RH, Cassidy A, Johnston KL, Myhill L, Hayward L, Wanji S, Turner JD, Taylor MJ, Ward SA. Aljayyoussi G, et al. Among authors: waterhouse d. Sci Rep. 2017 Mar 16;7(1):210. doi: 10.1038/s41598-017-00322-5. Sci Rep. 2017. PMID: 28303006 Free PMC article.
Pharmacokinetics of Antituberculosis Drugs in HIV-Positive and HIV-Negative Adults in Malawi.
van Oosterhout JJ, Dzinjalamala FK, Dimba A, Waterhouse D, Davies G, Zijlstra EE, Molyneux ME, Molyneux EM, Ward S. van Oosterhout JJ, et al. Among authors: waterhouse d. Antimicrob Agents Chemother. 2015 Oct;59(10):6175-80. doi: 10.1128/AAC.01193-15. Epub 2015 Jul 27. Antimicrob Agents Chemother. 2015. PMID: 26248378 Free PMC article. Clinical Trial.
Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis.
Sharma R, Al Jayoussi G, Tyrer HE, Gamble J, Hayward L, Guimaraes AF, Davies J, Waterhouse D, Cook DA, Myhill LJ, Clare RH, Cassidy A, Steven A, Johnston KL, Ford L, Turner JD, Ward SA, Taylor MJ. Sharma R, et al. Among authors: waterhouse d. Sci Rep. 2016 Mar 21;6:23458. doi: 10.1038/srep23458. Sci Rep. 2016. PMID: 26996237 Free PMC article.
Population Pharmacokinetics and Pharmacodynamics of Praziquantel in Ugandan Children with Intestinal Schistosomiasis: Higher Dosages Are Required for Maximal Efficacy.
Bustinduy AL, Waterhouse D, de Sousa-Figueiredo JC, Roberts SA, Atuhaire A, Van Dam GJ, Corstjens PL, Scott JT, Stanton MC, Kabatereine NB, Ward S, Hope WW, Stothard JR. Bustinduy AL, et al. Among authors: waterhouse d. mBio. 2016 Aug 9;7(4):e00227-16. doi: 10.1128/mBio.00227-16. mBio. 2016. PMID: 27507822 Free PMC article.
Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis.
Turner JD, Sharma R, Al Jayoussi G, Tyrer HE, Gamble J, Hayward L, Priestley RS, Murphy EA, Davies J, Waterhouse D, Cook DAN, Clare RH, Cassidy A, Steven A, Johnston KL, McCall J, Ford L, Hemingway J, Ward SA, Taylor MJ. Turner JD, et al. Among authors: waterhouse d. Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9712-E9721. doi: 10.1073/pnas.1710845114. Epub 2017 Oct 23. Proc Natl Acad Sci U S A. 2017. PMID: 29078351 Free PMC article.
259 results