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Deletion of the lifespan determinant p66(Shc) improves performance in a spatial memory task, decreases levels of oxidative stress markers in the hippocampus and increases levels of the neurotrophin BDNF in adult mice.
Berry A, Greco A, Giorgio M, Pelicci PG, de Kloet R, Alleva E, Minghetti L, Cirulli F. Berry A, et al. Among authors: alleva e. Exp Gerontol. 2008 Mar;43(3):200-8. doi: 10.1016/j.exger.2007.10.016. Epub 2007 Nov 7. Exp Gerontol. 2008. PMID: 18065182
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