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Mepivacaine-induced contraction involves phosphorylation of extracellular signal-regulated kinase through activation of the lipoxygenase pathway in isolated rat aortic smooth muscle.
Lee HM, Ok SH, Sung HJ, Eun SY, Kim HJ, Lee SH, Kang S, Shin IW, Lee HK, Chung YK, Choi MJ, Bae SI, Sohn JT. Lee HM, et al. Among authors: lee sh, lee hk. Can J Physiol Pharmacol. 2013 Apr;91(4):285-94. doi: 10.1139/cjpp-2012-0197. Epub 2013 Jan 2. Can J Physiol Pharmacol. 2013. PMID: 23627840
Lipid Emulsion Attenuates Acetylcholine-Induced Relaxation in Isolated Rat Aorta.
Ok SH, Lee SH, Yu J, Park J, Shin IW, Lee Y, Cho H, Choi MJ, Baik J, Hong JM, Han JY, Lee HK, Chung YK, Sohn JT. Ok SH, et al. Among authors: lee sh, lee y, lee hk. Biomed Res Int. 2015;2015:871545. doi: 10.1155/2015/871545. Epub 2015 Jul 27. Biomed Res Int. 2015. PMID: 26273653 Free PMC article.
Lipid emulsion inhibits vasodilation induced by a toxic dose of bupivacaine by suppressing bupivacaine-induced PKC and CPI-17 dephosphorylation but has no effect on vasodilation induced by a toxic dose of mepivacaine.
Cho H, Ok SH, Kwon SC, Lee SH, Baik J, Kang S, Oh J, Sohn JT. Cho H, et al. Among authors: lee sh. Korean J Pain. 2016 Oct;29(4):229-238. doi: 10.3344/kjp.2016.29.4.229. Epub 2016 Sep 29. Korean J Pain. 2016. PMID: 27738501 Free PMC article.
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