Quintás-Cardama A - Search Results

1

p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer.

Jackson JG, Pant V, Li Q, Chang LL, Quintás-Cardama A, Garza D, Tavana O, Yang P, Manshouri T, Li Y, El-Naggar AK, Lozano G. Jackson JG, et al. Cancer Cell. 2012 Jun 12;21(6):793-806. doi: 10.1016/j.ccr.2012.04.027. Cancer Cell. 2012. PMID: 22698404 Free PMC article.

2

The p53 pathway in hematopoiesis: lessons from mouse models, implications for humans.

Pant V, Quintás-Cardama A, Lozano G. Pant V, et al. Blood. 2012 Dec 20;120(26):5118-27. doi: 10.1182/blood-2012-05-356014. Epub 2012 Sep 27. Blood. 2012. PMID: 23018641 Free PMC article. Review.

3

A high-frequency regulatory polymorphism in the p53 pathway accelerates tumor development.

Post SM, Quintás-Cardama A, Pant V, Iwakuma T, Hamir A, Jackson JG, Maccio DR, Bond GL, Johnson DG, Levine AJ, Lozano G. Post SM, et al. Cancer Cell. 2010 Sep 14;18(3):220-30. doi: 10.1016/j.ccr.2010.07.010. Cancer Cell. 2010. PMID: 20832750 Free PMC article.

4

Restoring expression of wild-type p53 suppresses tumor growth but does not cause tumor regression in mice with a p53 missense mutation.

Wang Y, Suh YA, Fuller MY, Jackson JG, Xiong S, Terzian T, Quintás-Cardama A, Bankson JA, El-Naggar AK, Lozano G. Wang Y, et al. J Clin Invest. 2011 Mar;121(3):893-904. doi: 10.1172/JCI44504. J Clin Invest. 2011. PMID: 21285512 Free PMC article.

5

p53-dependent senescence delays Emu-myc-induced B-cell lymphomagenesis.

Post SM, Quintás-Cardama A, Terzian T, Smith C, Eischen CM, Lozano G. Post SM, et al. Oncogene. 2010 Mar 4;29(9):1260-9. doi: 10.1038/onc.2009.423. Epub 2009 Nov 23. Oncogene. 2010. PMID: 19935700 Free PMC article.

6

Sensitivity of human cells bearing oncogenic mutant kit isoforms to the novel tyrosine kinase inhibitor INNO-406.

Pan J, Quintás-Cardama A, Manshouri T, Cortes J, Kantarjian H, Verstovsek S. Pan J, et al. Cancer Sci. 2007 Aug;98(8):1223-5. doi: 10.1111/j.1349-7006.2007.00516.x. Epub 2007 May 22. Cancer Sci. 2007. PMID: 17517053 Free PMC article.

7

Bone marrow stroma-secreted cytokines protect JAK2(V617F)-mutated cells from the effects of a JAK2 inhibitor.

Manshouri T, Estrov Z, Quintás-Cardama A, Burger J, Zhang Y, Livun A, Knez L, Harris D, Creighton CJ, Kantarjian HM, Verstovsek S. Manshouri T, et al. Cancer Res. 2011 Jun 1;71(11):3831-40. doi: 10.1158/0008-5472.CAN-10-4002. Epub 2011 Apr 21. Cancer Res. 2011. PMID: 21512135 Free PMC article.

8

The p53-Mdm2 feedback loop protects against DNA damage by inhibiting p53 activity but is dispensable for p53 stability, development, and longevity.

Pant V, Xiong S, Jackson JG, Post SM, Abbas HA, Quintás-Cardama A, Hamir AN, Lozano G. Pant V, et al. Genes Dev. 2013 Sep 1;27(17):1857-67. doi: 10.1101/gad.227249.113. Epub 2013 Aug 23. Genes Dev. 2013. PMID: 23973961 Free PMC article.

9

Loss of the novel tumour suppressor and polarity gene Trim62 (Dear1) synergizes with oncogenic Ras in invasive lung cancer.

Quintás-Cardama A, Post SM, Solis LM, Xiong S, Yang P, Chen N, Wistuba II, Killary AM, Lozano G. Quintás-Cardama A, et al. J Pathol. 2014 Sep;234(1):108-19. doi: 10.1002/path.4385. Epub 2014 Jul 16. J Pathol. 2014. PMID: 24890125 Free PMC article.

10

hnRNP K Is a Haploinsufficient Tumor Suppressor that Regulates Proliferation and Differentiation Programs in Hematologic Malignancies.

Gallardo M, Lee HJ, Zhang X, Bueso-Ramos C, Pageon LR, McArthur M, Multani A, Nazha A, Manshouri T, Parker-Thornburg J, Rapado I, Quintas-Cardama A, Kornblau SM, Martinez-Lopez J, Post SM. Gallardo M, et al. Cancer Cell. 2015 Oct 12;28(4):486-499. doi: 10.1016/j.ccell.2015.09.001. Epub 2015 Sep 24. Cancer Cell. 2015. PMID: 26412324 Free PMC article.

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