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Use of whole-blood transcriptomic profiling to highlight several pathophysiologic pathways associated with response to rituximab in patients with rheumatoid arthritis: data from a randomized, controlled, open-label trial.
Sellam J, Marion-Thore S, Dumont F, Jacques S, Garchon HJ, Rouanet S, Taoufik Y, Hendel-Chavez H, Sibilia J, Tebib J, Le Loët X, Combe B, Dougados M, Mariette X, Chiocchia G. Sellam J, et al. Among authors: jacques s. Arthritis Rheumatol. 2014 Aug;66(8):2015-25. doi: 10.1002/art.38671. Arthritis Rheumatol. 2014. PMID: 24756903 Clinical Trial.
Investigation of the hepatotoxicity of flutamide: pro-survival/apoptotic and necrotic switch in primary rat hepatocytes characterized by metabolic and transcriptomic profiles in microfluidic liver biochips.
Legendre A, Jacques S, Dumont F, Cotton J, Paullier P, Fleury MJ, Leclerc E. Legendre A, et al. Among authors: jacques s. Toxicol In Vitro. 2014 Aug;28(5):1075-87. doi: 10.1016/j.tiv.2014.04.008. Epub 2014 Apr 30. Toxicol In Vitro. 2014. PMID: 24793618
Discovery and validation of a transcriptional signature identifying homologous recombination-deficient breast, endometrial and ovarian cancers.
Beinse G, Just PA, Le Frere Belda MA, Laurent-Puig P, Jacques S, Koual M, Garinet S, Leroy K, Delanoy N, Blons H, Gervais C, Durdux C, Chapron C, Goldwasser F, Terris B, Badoual C, Taly V, Bats AS, Borghese B, Alexandre J. Beinse G, et al. Among authors: jacques s. Br J Cancer. 2022 Oct;127(6):1123-1132. doi: 10.1038/s41416-022-01900-9. Epub 2022 Jun 25. Br J Cancer. 2022. PMID: 35752712 Free PMC article.
AhR-deficiency as a cause of demyelinating disease and inflammation.
Juricek L, Carcaud J, Pelhaitre A, Riday TT, Chevallier A, Lanzini J, Auzeil N, Laprévote O, Dumont F, Jacques S, Letourneur F, Massaad C, Agulhon C, Barouki R, Beraneck M, Coumoul X. Juricek L, et al. Among authors: jacques s. Sci Rep. 2017 Aug 29;7(1):9794. doi: 10.1038/s41598-017-09621-3. Sci Rep. 2017. PMID: 28851966 Free PMC article.
EZH1/2 function mostly within canonical PRC2 and exhibit proliferation-dependent redundancy that shapes mutational signatures in cancer.
Wassef M, Luscan A, Aflaki S, Zielinski D, Jansen PWTC, Baymaz HI, Battistella A, Kersouani C, Servant N, Wallace MR, Romero P, Kosmider O, Just PA, Hivelin M, Jacques S, Vincent-Salomon A, Vermeulen M, Vidaud M, Pasmant E, Margueron R. Wassef M, et al. Among authors: jacques s. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6075-6080. doi: 10.1073/pnas.1814634116. Epub 2019 Mar 13. Proc Natl Acad Sci U S A. 2019. PMID: 30867289 Free PMC article.
Essential role for autophagy protein ATG7 in the maintenance of intestinal stem cell integrity.
Trentesaux C, Fraudeau M, Pitasi CL, Lemarchand J, Jacques S, Duche A, Letourneur F, Naser E, Bailly K, Schmitt A, Perret C, Romagnolo B. Trentesaux C, et al. Among authors: jacques s. Proc Natl Acad Sci U S A. 2020 May 19;117(20):11136-11146. doi: 10.1073/pnas.1917174117. Epub 2020 May 5. Proc Natl Acad Sci U S A. 2020. PMID: 32371487 Free PMC article.
594 results