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Key findings and clinical implications from The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study.
Chipps BE, Zeiger RS, Borish L, Wenzel SE, Yegin A, Hayden ML, Miller DP, Bleecker ER, Simons FE, Szefler SJ, Weiss ST, Haselkorn T; TENOR Study Group. Chipps BE, et al. Among authors: bleecker er. J Allergy Clin Immunol. 2012 Aug;130(2):332-42.e10. doi: 10.1016/j.jaci.2012.04.014. Epub 2012 Jun 12. J Allergy Clin Immunol. 2012. PMID: 22694932 Free PMC article.
Asthma pharmacogenomics.
Hawkins GA, Weiss ST, Bleecker ER. Hawkins GA, et al. Among authors: bleecker er. Immunol Allergy Clin North Am. 2005 Nov;25(4):723-42. doi: 10.1016/j.iac.2005.09.004. Immunol Allergy Clin North Am. 2005. PMID: 16257635
Overview of the pharmacogenetics of asthma treatment.
Weiss ST, Litonjua AA, Lange C, Lazarus R, Liggett SB, Bleecker ER, Tantisira KG. Weiss ST, et al. Among authors: bleecker er. Pharmacogenomics J. 2006 Sep-Oct;6(5):311-26. doi: 10.1038/sj.tpj.6500387. Epub 2006 Apr 25. Pharmacogenomics J. 2006. PMID: 16568148 Review.
IL4R alpha mutations are associated with asthma exacerbations and mast cell/IgE expression.
Wenzel SE, Balzar S, Ampleford E, Hawkins GA, Busse WW, Calhoun WJ, Castro M, Chung KF, Erzurum S, Gaston B, Israel E, Teague WG, Curran-Everett D, Meyers DA, Bleecker ER. Wenzel SE, et al. Among authors: bleecker er. Am J Respir Crit Care Med. 2007 Mar 15;175(6):570-6. doi: 10.1164/rccm.200607-909OC. Epub 2006 Dec 14. Am J Respir Crit Care Med. 2007. PMID: 17170387 Free PMC article.
Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.
Moore WC, Bleecker ER, Curran-Everett D, Erzurum SC, Ameredes BT, Bacharier L, Calhoun WJ, Castro M, Chung KF, Clark MP, Dweik RA, Fitzpatrick AM, Gaston B, Hew M, Hussain I, Jarjour NN, Israel E, Levy BD, Murphy JR, Peters SP, Teague WG, Meyers DA, Busse WW, Wenzel SE; National Heart, Lung, Blood Institute's Severe Asthma Research Program. Moore WC, et al. Among authors: bleecker er. J Allergy Clin Immunol. 2007 Feb;119(2):405-13. doi: 10.1016/j.jaci.2006.11.639. J Allergy Clin Immunol. 2007. PMID: 17291857 Free PMC article.
Clinical consequences of ADRbeta2 polymorphisms.
Hawkins GA, Weiss ST, Bleecker ER. Hawkins GA, et al. Among authors: bleecker er. Pharmacogenomics. 2008 Mar;9(3):349-58. doi: 10.2217/14622416.9.3.349. Pharmacogenomics. 2008. PMID: 18303970 Review.
The glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroids.
Hawkins GA, Lazarus R, Smith RS, Tantisira KG, Meyers DA, Peters SP, Weiss ST, Bleecker ER. Hawkins GA, et al. Among authors: bleecker er. J Allergy Clin Immunol. 2009 Jun;123(6):1376-83.e7. doi: 10.1016/j.jaci.2009.01.049. Epub 2009 Feb 28. J Allergy Clin Immunol. 2009. PMID: 19254810 Free PMC article.
Consistently very poorly controlled asthma, as defined by the impairment domain of the Expert Panel Report 3 guidelines, increases risk for future severe asthma exacerbations in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study.
Haselkorn T, Fish JE, Zeiger RS, Szefler SJ, Miller DP, Chipps BE, Simons FE, Weiss ST, Wenzel SE, Borish L, Bleecker ER; TENOR Study Group. Haselkorn T, et al. Among authors: bleecker er. J Allergy Clin Immunol. 2009 Nov;124(5):895-902.e1-4. doi: 10.1016/j.jaci.2009.07.035. Epub 2009 Oct 7. J Allergy Clin Immunol. 2009. PMID: 19811812
503 results