Chetwyn NP - Search Results

1

Degradation of a pharmaceutical in HPLC grade methanol containing trace level formaldehyde.

Zhong Q, Stowers S, Segraves NL, Ngim KK, Zhang K, Bostick T, Deese A, Chetwyn NP. Zhong Q, et al. Among authors: chetwyn np. Pharm Dev Technol. 2013 Jul-Aug;18(4):877-82. doi: 10.3109/10837450.2012.696265. Epub 2012 Jun 12. Pharm Dev Technol. 2013. PMID: 22686350

2

Strategies for the analysis of highly reactive pinacolboronate esters.

Zhong Q, Ngim KK, Sun M, Li J, Deese A, Chetwyn NP. Zhong Q, et al. Among authors: chetwyn np. J Chromatogr A. 2012 Mar 16;1229:216-22. doi: 10.1016/j.chroma.2012.01.050. Epub 2012 Jan 25. J Chromatogr A. 2012. PMID: 22321949

3

Simultaneous determination of positive and negative pharmaceutical counterions using mixed-mode chromatography coupled with charged aerosol detector.

Zhang K, Dai L, Chetwyn NP. Zhang K, et al. Among authors: chetwyn np. J Chromatogr A. 2010 Sep 10;1217(37):5776-84. doi: 10.1016/j.chroma.2010.07.035. Epub 2010 Jul 21. J Chromatogr A. 2010. PMID: 20692668

4

Determination of trace level genotoxic impurities in small molecule drug substances using conventional headspace gas chromatography with contemporary ionic liquid diluents and electron capture detection.

Ho TD, Yehl PM, Chetwyn NP, Wang J, Anderson JL, Zhong Q. Ho TD, et al. Among authors: chetwyn np. J Chromatogr A. 2014 Sep 26;1361:217-28. doi: 10.1016/j.chroma.2014.07.099. Epub 2014 Aug 7. J Chromatogr A. 2014. PMID: 25151038

5

Limiting degradation of reactive antibody drug conjugate intermediates in HPLC method development.

Li Y, Medley CD, Zhang K, Wigman L, Chetwyn N. Li Y, et al. J Pharm Biomed Anal. 2014 Apr;92:114-8. doi: 10.1016/j.jpba.2014.01.004. Epub 2014 Jan 10. J Pharm Biomed Anal. 2014. PMID: 24503199

6

Analysis of pharmaceutical impurities using multi-heartcutting 2D LC coupled with UV-charged aerosol MS detection.

Zhang K, Li Y, Tsang M, Chetwyn NP. Zhang K, et al. Among authors: chetwyn np. J Sep Sci. 2013 Sep;36(18):2986-92. doi: 10.1002/jssc.201300493. Epub 2013 Jul 31. J Sep Sci. 2013. PMID: 23821312

7

A size exclusion-reversed phase two dimensional-liquid chromatography methodology for stability and small molecule related species in antibody drug conjugates.

Li Y, Gu C, Gruenhagen J, Zhang K, Yehl P, Chetwyn NP, Medley CD. Li Y, et al. Among authors: chetwyn np. J Chromatogr A. 2015 May 8;1393:81-8. doi: 10.1016/j.chroma.2015.03.027. Epub 2015 Mar 16. J Chromatogr A. 2015. PMID: 25818558

8

Quantification of residual solvents in antibody drug conjugates using gas chromatography.

Medley CD, Kay J, Li Y, Gruenhagen J, Yehl P, Chetwyn NP. Medley CD, et al. Among authors: chetwyn np. Anal Chim Acta. 2014 Nov 19;850:92-6. doi: 10.1016/j.aca.2014.09.003. Epub 2014 Sep 8. Anal Chim Acta. 2014. PMID: 25441165

9

An enzymatic deconjugation method for the analysis of small molecule active drugs on antibody-drug conjugates.

Li Y, Gu C, Gruenhagen J, Yehl P, Chetwyn NP, Medley CD. Li Y, et al. Among authors: chetwyn np. MAbs. 2016 May-Jun;8(4):698-705. doi: 10.1080/19420862.2016.1151590. Epub 2016 Feb 18. MAbs. 2016. PMID: 26891281 Free PMC article.

10

A DNA-conjugated magnetic nanoparticle assay for assessing genotoxicity.

Medley CD, Smith JE, Wigman LS, Chetwyn NP. Medley CD, et al. Among authors: chetwyn np. Anal Bioanal Chem. 2012 Nov;404(8):2233-9. doi: 10.1007/s00216-012-6350-7. Epub 2012 Aug 24. Anal Bioanal Chem. 2012. PMID: 22918539

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