Reddy EP - Search Results

1

Preclinical pharmacokinetic and pharmacodynamic evaluation of novel anticancer agents, ON01910.Na (Rigosertib, Estybon™) and ON013105, for brain tumor chemotherapy.

Nuthalapati S, Zhou Q, Guo P, Lv H, Cosenza S, Reddy MV, Reddy EP, Gallo JM. Nuthalapati S, et al. Among authors: reddy mv, reddy ep. Pharm Res. 2012 Sep;29(9):2499-511. doi: 10.1007/s11095-012-0780-y. Epub 2012 Jun 8. Pharm Res. 2012. PMID: 22678771

2

Application of a liquid chromatography-tandem mass spectrometry (LC/MS/MS) method to the pharmacokinetics of ON01910 in brain tumor-bearing mice.

Nuthalapati S, Guo P, Zhou Q, Reddy MV, Reddy EP, Gallo JM. Nuthalapati S, et al. Among authors: reddy mv, reddy ep. J Pharm Biomed Anal. 2011 Dec 15;56(5):1117-20. doi: 10.1016/j.jpba.2011.08.003. Epub 2011 Aug 9. J Pharm Biomed Anal. 2011. PMID: 21880454 Free PMC article.

3

Preclinical pharmacological evaluation of a novel multiple kinase inhibitor, ON123300, in brain tumor models.

Zhang X, Lv H, Zhou Q, Elkholi R, Chipuk JE, Reddy MV, Reddy EP, Gallo JM. Zhang X, et al. Among authors: reddy mv, reddy ep. Mol Cancer Ther. 2014 May;13(5):1105-16. doi: 10.1158/1535-7163.MCT-13-0847. Epub 2014 Feb 25. Mol Cancer Ther. 2014. PMID: 24568969 Free PMC article.

4

ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent.

Gumireddy K, Reddy MV, Cosenza SC, Boominathan R, Baker SJ, Papathi N, Jiang J, Holland J, Reddy EP. Gumireddy K, et al. Among authors: reddy mv, reddy ep. Cancer Cell. 2005 Mar;7(3):275-86. doi: 10.1016/j.ccr.2005.02.009. Cancer Cell. 2005. PMID: 15766665 Free article.

5

Design, synthesis, and biological evaluation of (E)-styrylbenzylsulfones as novel anticancer agents.

Reddy MV, Mallireddigari MR, Cosenza SC, Pallela VR, Iqbal NM, Robell KA, Kang AD, Reddy EP. Reddy MV, et al. Among authors: reddy ep. J Med Chem. 2008 Jan 10;51(1):86-100. doi: 10.1021/jm701077b. Epub 2007 Dec 19. J Med Chem. 2008. PMID: 18088089

6

Screening candidate anticancer drugs for brain tumor chemotherapy: pharmacokinetic-driven approach for a series of (E)-N-(substituted aryl)-3-(substituted phenyl)propenamide analogues.

Lv H, Wang F, Reddy MV, Zhou Q, Zhang X, Reddy EP, Gallo JM. Lv H, et al. Among authors: reddy mv, reddy ep. Invest New Drugs. 2012 Dec;30(6):2263-73. doi: 10.1007/s10637-012-9806-x. Epub 2012 Mar 1. Invest New Drugs. 2012. PMID: 22383114 Free PMC article.

7

Integrated pharmacokinetic-driven approach to screen candidate anticancer drugs for brain tumor chemotherapy.

Lv H, Zhang X, Sharma J, Reddy MV, Reddy EP, Gallo JM. Lv H, et al. Among authors: reddy mv, reddy ep. AAPS J. 2013 Jan;15(1):250-7. doi: 10.1208/s12248-012-9428-4. Epub 2012 Nov 22. AAPS J. 2013. PMID: 23180160 Free PMC article.

8

Determination of the glucuronide metabolite of ON 013100, a benzylstyrylsulfone antineoplastic drug, in colon cancer cells using LC/MS/MS.

Cho SY, Cosenza SC, Pallela V, Panda G, Reddy MV, Reddy EP, Roboz J. Cho SY, et al. Among authors: reddy mv, reddy ep. J Pharm Biomed Anal. 2013 Mar 5;75:138-44. doi: 10.1016/j.jpba.2012.11.022. Epub 2012 Nov 23. J Pharm Biomed Anal. 2013. PMID: 23261806 Free PMC article.

9

Design, synthesis, and biological evaluation of (E)-N-aryl-2-arylethenesulfonamide analogues as potent and orally bioavailable microtubule-targeted anticancer agents.

Reddy MV, Mallireddigari MR, Pallela VR, Cosenza SC, Billa VK, Akula B, Subbaiah DR, Bharathi EV, Padgaonkar A, Lv H, Gallo JM, Reddy EP. Reddy MV, et al. Among authors: reddy ep. J Med Chem. 2013 Jul 11;56(13):5562-86. doi: 10.1021/jm400575x. Epub 2013 Jun 25. J Med Chem. 2013. PMID: 23750455 Free PMC article.

10

Synthesis of new coumarin 3-(N-aryl) sulfonamides and their anticancer activity.

Reddy NS, Mallireddigari MR, Cosenza S, Gumireddy K, Bell SC, Reddy EP, Reddy MV. Reddy NS, et al. Among authors: reddy mv, reddy ep. Bioorg Med Chem Lett. 2004 Aug 2;14(15):4093-7. doi: 10.1016/j.bmcl.2004.05.016. Bioorg Med Chem Lett. 2004. PMID: 15225733

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