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Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4.
Allam R, Scherbaum CR, Darisipudi MN, Mulay SR, Hägele H, Lichtnekert J, Hagemann JH, Rupanagudi KV, Ryu M, Schwarzenberger C, Hohenstein B, Hugo C, Uhl B, Reichel CA, Krombach F, Monestier M, Liapis H, Moreth K, Schaefer L, Anders HJ. Allam R, et al. Among authors: krombach f. J Am Soc Nephrol. 2012 Aug;23(8):1375-88. doi: 10.1681/ASN.2011111077. Epub 2012 Jun 7. J Am Soc Nephrol. 2012. PMID: 22677551 Free PMC article.
Delayed chemokine receptor 1 blockade prolongs survival in collagen 4A3-deficient mice with Alport disease.
Ninichuk V, Gross O, Reichel C, Khandoga A, Pawar RD, Ciubar R, Segerer S, Belemezova E, Radomska E, Luckow B, Perez de Lema G, Murphy PM, Gao JL, Henger A, Kretzler M, Horuk R, Weber M, Krombach F, Schlöndorff D, Anders HJ. Ninichuk V, et al. Among authors: krombach f. J Am Soc Nephrol. 2005 Apr;16(4):977-85. doi: 10.1681/ASN.2004100871. Epub 2005 Feb 16. J Am Soc Nephrol. 2005. PMID: 15716328
Synchronized renal tubular cell death involves ferroptosis.
Linkermann A, Skouta R, Himmerkus N, Mulay SR, Dewitz C, De Zen F, Prokai A, Zuchtriegel G, Krombach F, Welz PS, Weinlich R, Vanden Berghe T, Vandenabeele P, Pasparakis M, Bleich M, Weinberg JM, Reichel CA, Bräsen JH, Kunzendorf U, Anders HJ, Stockwell BR, Green DR, Krautwald S. Linkermann A, et al. Among authors: krombach f. Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16836-41. doi: 10.1073/pnas.1415518111. Epub 2014 Nov 10. Proc Natl Acad Sci U S A. 2014. PMID: 25385600 Free PMC article.
Tissue plasminogen activator promotes postischemic neutrophil recruitment via its proteolytic and nonproteolytic properties.
Uhl B, Zuchtriegel G, Puhr-Westerheide D, Praetner M, Rehberg M, Fabritius M, Hessenauer M, Holzer M, Khandoga A, Fürst R, Zahler S, Krombach F, Reichel CA. Uhl B, et al. Among authors: krombach f. Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1495-504. doi: 10.1161/ATVBAHA.114.303721. Epub 2014 Apr 24. Arterioscler Thromb Vasc Biol. 2014. PMID: 24764453
179 results