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On the mechanism of action of SJ-172550 in inhibiting the interaction of MDM4 and p53.
Bista M, Smithson D, Pecak A, Salinas G, Pustelny K, Min J, Pirog A, Finch K, Zdzalik M, Waddell B, Wladyka B, Kedracka-Krok S, Dyer MA, Dubin G, Guy RK. Bista M, et al. Among authors: waddell b. PLoS One. 2012;7(6):e37518. doi: 10.1371/journal.pone.0037518. Epub 2012 Jun 4. PLoS One. 2012. PMID: 22675482 Free PMC article.
Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors.
Shadrick WR, Slavish PJ, Chai SC, Waddell B, Connelly M, Low JA, Tallant C, Young BM, Bharatham N, Knapp S, Boyd VA, Morfouace M, Roussel MF, Chen T, Lee RE, Kiplin Guy R, Shelat AA, Potter PM. Shadrick WR, et al. Among authors: waddell b. Bioorg Med Chem. 2018 Jan 1;26(1):25-36. doi: 10.1016/j.bmc.2017.10.042. Epub 2017 Nov 4. Bioorg Med Chem. 2018. PMID: 29170024 Free PMC article.
The airway microbiome of persons with cystic fibrosis correlates with acquisition and microbiological outcomes of incident Stenotrophomonas maltophilia infection.
Bowron LA, Acosta N, Thornton CS, Carpentero J, Waddell BM, Bharadwaj L, Ebbert K, Castañeda-Mogollón D, Conly JM, Rabin HR, Surette MG, Parkins MD. Bowron LA, et al. Among authors: waddell bm. Front Microbiol. 2024 Apr 16;15:1353145. doi: 10.3389/fmicb.2024.1353145. eCollection 2024. Front Microbiol. 2024. PMID: 38690371 Free PMC article.
Porcine-derived pancreatic enzyme replacement therapy may be linked to chronic hepatitis E virus infection in cystic fibrosis lung transplant recipients.
Thornton CS, Waddell BJ, Congly SE, Svishchuk J, Somayaji R, Fatovich L, Isaac D, Doucette K, Fonseca K, Drews SJ, Borlang J, Osiowy C, Parkins MD. Thornton CS, et al. Among authors: waddell bj. Gut. 2024 Sep 9;73(10):1702-1711. doi: 10.1136/gutjnl-2023-330602. Gut. 2024. PMID: 38621922 Free PMC article.
227 results