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Indoleamine 2,3-dioxygenase 1 (IDO1) is up-regulated in thyroid carcinoma and drives the development of an immunosuppressant tumor microenvironment.
Moretti S, Menicali E, Voce P, Morelli S, Cantarelli S, Sponziello M, Colella R, Fallarino F, Orabona C, Alunno A, de Biase D, Bini V, Mameli MG, Filetti S, Gerli R, Macchiarulo A, Melillo RM, Tallini G, Santoro M, Puccetti P, Avenia N, Puxeddu E. Moretti S, et al. Among authors: menicali e. J Clin Endocrinol Metab. 2014 May;99(5):E832-40. doi: 10.1210/jc.2013-3351. Epub 2014 Feb 11. J Clin Endocrinol Metab. 2014. PMID: 24517146
Immune Landscape of Thyroid Cancers: New Insights.
Menicali E, Guzzetti M, Morelli S, Moretti S, Puxeddu E. Menicali E, et al. Front Endocrinol (Lausanne). 2021 Apr 27;11:637826. doi: 10.3389/fendo.2020.637826. eCollection 2020. Front Endocrinol (Lausanne). 2021. PMID: 33986723 Free PMC article. Review.
Signal Transducer and Activator of Transcription 1 Plays a Pivotal Role in RET/PTC3 Oncogene-induced Expression of Indoleamine 2,3-Dioxygenase 1.
Moretti S, Menicali E, Nucci N, Voce P, Colella R, Melillo RM, Liotti F, Morelli S, Fallarino F, Macchiarulo A, Santoro M, Avenia N, Puxeddu E. Moretti S, et al. Among authors: menicali e. J Biol Chem. 2017 Feb 3;292(5):1785-1797. doi: 10.1074/jbc.M116.745448. Epub 2016 Dec 19. J Biol Chem. 2017. PMID: 27994058 Free PMC article.