Espinosa JM - Search Results

1

ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53.

Sullivan KD, Padilla-Just N, Henry RE, Porter CC, Kim J, Tentler JJ, Eckhardt SG, Tan AC, DeGregori J, Espinosa JM. Sullivan KD, et al. Among authors: espinosa jm. Nat Chem Biol. 2012 Jul;8(7):646-54. doi: 10.1038/nchembio.965. Epub 2012 Jun 3. Nat Chem Biol. 2012. PMID: 22660439 Free PMC article.

2

CDK8 is a stimulus-specific positive coregulator of p53 target genes.

Donner AJ, Szostek S, Hoover JM, Espinosa JM. Donner AJ, et al. Among authors: espinosa jm. Mol Cell. 2007 Jul 6;27(1):121-33. doi: 10.1016/j.molcel.2007.05.026. Mol Cell. 2007. PMID: 17612495 Free PMC article.

3

Stimulus-specific transcriptional regulation within the p53 network.

Donner AJ, Hoover JM, Szostek SA, Espinosa JM. Donner AJ, et al. Among authors: espinosa jm. Cell Cycle. 2007 Nov 1;6(21):2594-8. doi: 10.4161/cc.6.21.4893. Epub 2007 Aug 13. Cell Cycle. 2007. PMID: 17957141 Free PMC article.

4

Mechanisms of regulatory diversity within the p53 transcriptional network.

Espinosa JM. Espinosa JM. Oncogene. 2008 Jul 3;27(29):4013-23. doi: 10.1038/onc.2008.37. Epub 2008 Feb 18. Oncogene. 2008. PMID: 18278067 Free PMC article.

5

Multiple p53-independent gene silencing mechanisms define the cellular response to p53 activation.

París R, Henry RE, Stephens SJ, McBryde M, Espinosa JM. París R, et al. Among authors: espinosa jm. Cell Cycle. 2008 Aug;7(15):2427-33. doi: 10.4161/cc.6420. Epub 2008 Jun 9. Cell Cycle. 2008. PMID: 18677110 Free PMC article.

6

Differential regulation of p53 target genes: it's (core promoter) elementary.

Gomes NP, Espinosa JM. Gomes NP, et al. Among authors: espinosa jm. Genes Dev. 2010 Jan 15;24(2):111-4. doi: 10.1101/gad.1893610. Genes Dev. 2010. PMID: 20080948 Free PMC article.

7

Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding.

Gomes NP, Espinosa JM. Gomes NP, et al. Among authors: espinosa jm. Genes Dev. 2010 May 15;24(10):1022-34. doi: 10.1101/gad.1881010. Genes Dev. 2010. PMID: 20478995 Free PMC article.

8

Disparate chromatin landscapes and kinetics of inactivation impact differential regulation of p53 target genes.

Gomes NP, Espinosa JM. Gomes NP, et al. Among authors: espinosa jm. Cell Cycle. 2010 Sep 1;9(17):3428-37. doi: 10.4161/cc.9.17.12998. Epub 2010 Sep 13. Cell Cycle. 2010. PMID: 20818159 Free PMC article.

9

A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX.

Henry RE, Andrysik Z, París R, Galbraith MD, Espinosa JM. Henry RE, et al. Among authors: espinosa jm. EMBO J. 2012 Mar 7;31(5):1266-78. doi: 10.1038/emboj.2011.498. Epub 2012 Jan 13. EMBO J. 2012. PMID: 22246181 Free PMC article.

10

The p53 circuit board.

Sullivan KD, Gallant-Behm CL, Henry RE, Fraikin JL, Espinosa JM. Sullivan KD, et al. Among authors: espinosa jm. Biochim Biophys Acta. 2012 Apr;1825(2):229-44. doi: 10.1016/j.bbcan.2012.01.004. Epub 2012 Feb 7. Biochim Biophys Acta. 2012. PMID: 22333261 Free PMC article. Review.

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