de Lederkremer RM - Search Results

1

Improved bioavailability of inhibitors of Trypanosoma cruzi trans-sialidase: PEGylation of lactose analogs with multiarm polyethyleneglycol.

Giorgi ME, Ratier L, Agusti R, Frasch AC, de Lederkremer RM. Giorgi ME, et al. Among authors: de lederkremer rm. Glycobiology. 2012 Oct;22(10):1363-73. doi: 10.1093/glycob/cws091. Epub 2012 May 30. Glycobiology. 2012. PMID: 22653661 Free PMC article.

2

Synthesis of the O-linked pentasaccharide in glycoproteins of Trypanosoma cruzi and selective sialylation by recombinant trans-sialidase.

Mendoza VM, Agusti R, Gallo-Rodriguez C, de Lederkremer RM. Mendoza VM, et al. Among authors: de lederkremer rm. Carbohydr Res. 2006 Jul 24;341(10):1488-97. doi: 10.1016/j.carres.2006.03.033. Epub 2006 Apr 21. Carbohydr Res. 2006. PMID: 16630598

3

Comparative rates of sialylation by recombinant trans-sialidase and inhibitor properties of synthetic oligosaccharides from Trypanosoma cruzi mucins-containing galactofuranose and galactopyranose.

Agustí R, Giorgi ME, Mendoza VM, Gallo-Rodriguez C, de Lederkremer RM. Agustí R, et al. Among authors: de lederkremer rm. Bioorg Med Chem. 2007 Apr 1;15(7):2611-6. doi: 10.1016/j.bmc.2007.01.045. Epub 2007 Jan 31. Bioorg Med Chem. 2007. PMID: 17292612

4

The trans-sialidase from Trypanosoma cruzi efficiently transfers alpha-(2-->3)-linked N-glycolylneuraminic acid to terminal beta-galactosyl units.

Agustí R, Giorgi ME, de Lederkremer RM. Agustí R, et al. Among authors: de lederkremer rm. Carbohydr Res. 2007 Nov 26;342(16):2465-9. doi: 10.1016/j.carres.2007.07.018. Epub 2007 Aug 2. Carbohydr Res. 2007. PMID: 17765882

5

Continuous nonradioactive method for screening trypanosomal trans-sialidase activity and its inhibitors.

Sartor PA, Agusti R, Leguizamón MS, Campetella O, de Lederkremer RM. Sartor PA, et al. Among authors: de lederkremer rm. Glycobiology. 2010 Aug;20(8):982-90. doi: 10.1093/glycob/cwq056. Epub 2010 Apr 7. Glycobiology. 2010. PMID: 20375068 Free PMC article.

6

Synthesis of PEGylated lactose analogs for inhibition studies on T.cruzi trans-sialidase.

Giorgi ME, Ratier L, Agusti R, Frasch AC, de Lederkremer RM. Giorgi ME, et al. Among authors: de lederkremer rm. Glycoconj J. 2010 Jul;27(5):549-59. doi: 10.1007/s10719-010-9300-7. Epub 2010 Jul 20. Glycoconj J. 2010. PMID: 20645127

7

Trans-sialidase and mucins of Trypanosoma cruzi: an important interplay for the parasite.

Giorgi ME, de Lederkremer RM. Giorgi ME, et al. Among authors: de lederkremer rm. Carbohydr Res. 2011 Sep 6;346(12):1389-93. doi: 10.1016/j.carres.2011.04.006. Epub 2011 Apr 8. Carbohydr Res. 2011. PMID: 21645882 Review.

8

Synthesis of the O-linked hexasaccharide containing β-D-Galp-(1→2)-D-Galf in Trypanosoma cruzi mucins. Differences on sialylation by trans-sialidase of the two constituent hexasaccharides.

Agustí R, Giorgi ME, Mendoza VM, Kashiwagi GA, de Lederkremer RM, Gallo-Rodriguez C. Agustí R, et al. Among authors: de lederkremer rm. Bioorg Med Chem. 2015 Mar 15;23(6):1213-22. doi: 10.1016/j.bmc.2015.01.056. Epub 2015 Feb 7. Bioorg Med Chem. 2015. PMID: 25703305

9

Multivalent sialylation of β-thio-glycoclusters by Trypanosoma cruzi trans sialidase and analysis by high performance anion exchange chromatography.

Agustí R, Cano ME, Cagnoni AJ, Kovensky J, de Lederkremer RM, Uhrig ML. Agustí R, et al. Among authors: de lederkremer rm. Glycoconj J. 2016 Oct;33(5):809-18. doi: 10.1007/s10719-016-9676-0. Epub 2016 Jun 15. Glycoconj J. 2016. PMID: 27306205

10

Synthesis of a model trisaccharide for studying the interplay between the anti α-Gal antibody and the trans-sialidase reactions in Trypanosoma cruzi.

Giorgi ME, Lopez R, Agusti R, Marino C, de Lederkremer RM. Giorgi ME, et al. Among authors: de lederkremer rm. Carbohydr Res. 2017 Oct 10;450:30-37. doi: 10.1016/j.carres.2017.08.007. Epub 2017 Aug 18. Carbohydr Res. 2017. PMID: 28858610

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