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GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia.
Greif PA, Dufour A, Konstandin NP, Ksienzyk B, Zellmeier E, Tizazu B, Sturm J, Benthaus T, Herold T, Yaghmaie M, Dörge P, Hopfner KP, Hauser A, Graf A, Krebs S, Blum H, Kakadia PM, Schneider S, Hoster E, Schneider F, Stanulla M, Braess J, Sauerland MC, Berdel WE, Büchner T, Woermann BJ, Hiddemann W, Spiekermann K, Bohlander SK. Greif PA, et al. Among authors: tizazu b. Blood. 2012 Jul 12;120(2):395-403. doi: 10.1182/blood-2012-01-403220. Epub 2012 May 30. Blood. 2012. PMID: 22649106 Free article. Clinical Trial.
The target cell of transformation is distinct from the leukemia stem cell in murine CALM/AF10 leukemia models.
Dutta S, Krause A, Vosberg S, Herold T, Ksienzyk B, Quintanilla-Martinez L, Tizazu B, Chopra M, Graf A, Krebs S, Blum H, Greif PA, Vetter A, Metzeler K, Rothenberg-Thurley M, Schneider MR, Dahlhoff M, Spiekermann K, Zimber-Strobl U, Wolf E, Bohlander SK. Dutta S, et al. Among authors: tizazu b. Leukemia. 2016 May;30(5):1166-76. doi: 10.1038/leu.2015.349. Epub 2015 Dec 21. Leukemia. 2016. PMID: 26686248
Loss of KDM6A confers drug resistance in acute myeloid leukemia.
Stief SM, Hanneforth AL, Weser S, Mattes R, Carlet M, Liu WH, Bartoschek MD, Domínguez Moreno H, Oettle M, Kempf J, Vick B, Ksienzyk B, Tizazu B, Rothenberg-Thurley M, Quentmeier H, Hiddemann W, Vosberg S, Greif PA, Metzeler KH, Schotta G, Bultmann S, Jeremias I, Leonhardt H, Spiekermann K. Stief SM, et al. Among authors: tizazu b. Leukemia. 2020 Jan;34(1):50-62. doi: 10.1038/s41375-019-0497-6. Epub 2019 Jun 14. Leukemia. 2020. PMID: 31201358 Free PMC article.
FHL2 interacts with CALM and is highly expressed in acute erythroid leukemia.
Pašaliç Z, Greif PA, Jurinoviç V, Mulaw M, Kakadia PM, Tizazu B, Fröhlich-Archangelo L, Krause A, Bohlander SK. Pašaliç Z, et al. Among authors: tizazu b. Blood Cancer J. 2011 Nov;1(11):e42. doi: 10.1038/bcj.2011.40. Epub 2011 Nov 11. Blood Cancer J. 2011. PMID: 22829078 Free PMC article.
15 results