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Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma.
Jacquelot N, Seillet C, Wang M, Pizzolla A, Liao Y, Hediyeh-Zadeh S, Grisaru-Tal S, Louis C, Huang Q, Schreuder J, Souza-Fonseca-Guimaraes F, de Graaf CA, Thia K, Macdonald S, Camilleri M, Luong K, Zhang S, Chopin M, Molden-Hauer T, Nutt SL, Umansky V, Ciric B, Groom JR, Foster PS, Hansbro PM, McKenzie ANJ, Gray DHD, Behren A, Cebon J, Vivier E, Wicks IP, Trapani JA, Munitz A, Davis MJ, Shi W, Neeson PJ, Belz GT. Jacquelot N, et al. Among authors: chopin m. Nat Immunol. 2021 Jul;22(7):851-864. doi: 10.1038/s41590-021-00943-z. Epub 2021 Jun 7. Nat Immunol. 2021. PMID: 34099918 Free PMC article.
Type 1 conventional dendritic cell fate and function are controlled by DC-SCRIPT.
Zhang S, Coughlan HD, Ashayeripanah M, Seizova S, Kueh AJ, Brown DV, Cao W, Jacquelot N, D'Amico A, Lew AM, Zhan Y, Tonkin CJ, Villadangos JA, Smyth GK, Chopin M, Nutt SL. Zhang S, et al. Among authors: chopin m. Sci Immunol. 2021 Apr 2;6(58):eabf4432. doi: 10.1126/sciimmunol.abf4432. Sci Immunol. 2021. PMID: 33811060
The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.
Carotta S, Willis SN, Hasbold J, Inouye M, Pang SH, Emslie D, Light A, Chopin M, Shi W, Wang H, Morse HC 3rd, Tarlinton DM, Corcoran LM, Hodgkin PD, Nutt SL. Carotta S, et al. Among authors: chopin m. J Exp Med. 2014 Oct 20;211(11):2169-81. doi: 10.1084/jem.20140425. Epub 2014 Oct 6. J Exp Med. 2014. PMID: 25288399 Free PMC article.
140 results