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Angiotensin II enhances AT1-Nox1 binding and stimulates arterial smooth muscle cell migration and proliferation through AT1, Nox1, and interleukin-18.
Valente AJ, Yoshida T, Murthy SN, Sakamuri SS, Katsuyama M, Clark RA, Delafontaine P, Chandrasekar B. Valente AJ, et al. Among authors: chandrasekar b. Am J Physiol Heart Circ Physiol. 2012 Aug 1;303(3):H282-96. doi: 10.1152/ajpheart.00231.2012. Epub 2012 May 25. Am J Physiol Heart Circ Physiol. 2012. PMID: 22636674 Free PMC article.
The pro-atherogenic cytokine interleukin-18 induces CXCL16 expression in rat aortic smooth muscle cells via MyD88, interleukin-1 receptor-associated kinase, tumor necrosis factor receptor-associated factor 6, c-Src, phosphatidylinositol 3-kinase, Akt, c-Jun N-terminal kinase, and activator protein-1 signaling.
Chandrasekar B, Mummidi S, Valente AJ, Patel DN, Bailey SR, Freeman GL, Hatano M, Tokuhisa T, Jensen LE. Chandrasekar B, et al. J Biol Chem. 2005 Jul 15;280(28):26263-77. doi: 10.1074/jbc.M502586200. Epub 2005 May 11. J Biol Chem. 2005. PMID: 15890643 Free article.
We recently demonstrated that the chemokine CXCL16 is expressed in aortic smooth muscle cells (ASMC) and induces ASMC adhesion and proliferation (Chandrasekar, B., Bysani, S., and Mummidi, S. (2004) J. Biol. Chem. 279, 3188-3196). Here we reort that interleukin (IL) …
We recently demonstrated that the chemokine CXCL16 is expressed in aortic smooth muscle cells (ASMC) and induces ASMC adhesion and prolifera …
Interleukin-18-induced human coronary artery smooth muscle cell migration is dependent on NF-kappaB- and AP-1-mediated matrix metalloproteinase-9 expression and is inhibited by atorvastatin.
Chandrasekar B, Mummidi S, Mahimainathan L, Patel DN, Bailey SR, Imam SZ, Greene WC, Valente AJ. Chandrasekar B, et al. J Biol Chem. 2006 Jun 2;281(22):15099-109. doi: 10.1074/jbc.M600200200. Epub 2006 Mar 22. J Biol Chem. 2006. PMID: 16554298 Free article.
Because we demonstrated previously that the proinflammatory and proatherogenic cytokine interleukin-18 (IL-18) stimulates SMC proliferation (Chandrasekar, B., Mummidi, S., Valente, A. J., Patel, D. N., Bailey, S. R., Freeman, G. L., Hatano, M., Tokuhisa, T., and Jen …
Because we demonstrated previously that the proinflammatory and proatherogenic cytokine interleukin-18 (IL-18) stimulates SMC proliferation …
TLR4-NOX4-AP-1 signaling mediates lipopolysaccharide-induced CXCR6 expression in human aortic smooth muscle cells.
Patel DN, Bailey SR, Gresham JK, Schuchman DB, Shelhamer JH, Goldstein BJ, Foxwell BM, Stemerman MB, Maranchie JK, Valente AJ, Mummidi S, Chandrasekar B. Patel DN, et al. Among authors: chandrasekar b. Biochem Biophys Res Commun. 2006 Sep 8;347(4):1113-20. doi: 10.1016/j.bbrc.2006.07.015. Epub 2006 Jul 13. Biochem Biophys Res Commun. 2006. PMID: 16870145
Wnt-induced secreted protein-1 is a prohypertrophic and profibrotic growth factor.
Colston JT, de la Rosa SD, Koehler M, Gonzales K, Mestril R, Freeman GL, Bailey SR, Chandrasekar B. Colston JT, et al. Among authors: chandrasekar b. Am J Physiol Heart Circ Physiol. 2007 Sep;293(3):H1839-46. doi: 10.1152/ajpheart.00428.2007. Epub 2007 Jul 6. Am J Physiol Heart Circ Physiol. 2007. PMID: 17616748 Free article.
IL-17 stimulates MMP-1 expression in primary human cardiac fibroblasts via p38 MAPK- and ERK1/2-dependent C/EBP-beta , NF-kappaB, and AP-1 activation.
Cortez DM, Feldman MD, Mummidi S, Valente AJ, Steffensen B, Vincenti M, Barnes JL, Chandrasekar B. Cortez DM, et al. Among authors: chandrasekar b. Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3356-65. doi: 10.1152/ajpheart.00928.2007. Epub 2007 Oct 5. Am J Physiol Heart Circ Physiol. 2007. PMID: 17921324 Free article.
237 results