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Page 1
Fused tricyclic indoles as S1P₁ agonists with robust efficacy in animal models of autoimmune disease.
Buzard DJ, Han S, Lopez L, Kawasaki A, Moody J, Thoresen L, Ullman B, Lehmann J, Calderon I, Zhu X, Gharbaoui T, Sengupta D, Krishnan A, Gao Y, Edwards J, Barden J, Morgan M, Usmani K, Chen C, Sadeque A, Thatte J, Solomon M, Fu L, Whelan K, Liu L, Al-Shamma H, Gatlin J, Le M, Xing C, Espinola S, Jones RM. Buzard DJ, et al. Among authors: krishnan a. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4404-9. doi: 10.1016/j.bmcl.2012.04.129. Epub 2012 May 7. Bioorg Med Chem Lett. 2012. PMID: 22633692
(7-Benzyloxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetic Acids as S1P1 Functional Antagonists.
Buzard DJ, Lopez L, Moody J, Kawasaki A, Schrader TO, Kasem M, Johnson B, Zhu X, Thoresen L, Kim SH, Gharbaoui T, Sengupta D, Calvano L, Krishnan A, Gao Y, Semple G, Edwards J, Barden J, Morgan M, Usmani K, Chen C, Sadeque A, Chen W, Christopher RJ, Thatte J, Fu L, Solomon M, Whelan K, Al-Shamma H, Gatlin J, Gaidarov I, Anthony T, Le M, Unett DJ, Stirn S, Blackburn A, Behan DP, Jones RM. Buzard DJ, et al. Among authors: krishnan a. ACS Med Chem Lett. 2014 Nov 25;5(12):1334-9. doi: 10.1021/ml500422m. eCollection 2014 Dec 11. ACS Med Chem Lett. 2014. PMID: 25516794 Free PMC article.
Discovery of 2-(((1r,4r)-4-(((4-Chlorophenyl)(phenyl)carbamoyl)oxy)methyl)cyclohexyl)methoxy)acetate (Ralinepag): An Orally Active Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension.
Tran TA, Kramer B, Shin YJ, Vallar P, Boatman PD, Zou N, Sage CR, Gharbaoui T, Krishnan A, Pal B, Shakya SR, Garrido Montalban A, Adams JW, Ramirez J, Behan DP, Shifrina A, Blackburn A, Leakakos T, Shi Y, Morgan M, Sadeque A, Chen W, Unett DJ, Gaidarov I, Chen X, Chang S, Shu HH, Tung SF, Semple G. Tran TA, et al. Among authors: krishnan a. J Med Chem. 2017 Feb 9;60(3):913-927. doi: 10.1021/acs.jmedchem.6b00871. Epub 2017 Jan 19. J Med Chem. 2017. PMID: 28072531 Free PMC article.
Ethnic and racial differences in children and young people with respiratory and neurological post-acute sequelae of SARS-CoV-2: an electronic health record-based cohort study from the RECOVER Initiative.
Rao S, Azuero-Dajud R, Lorman V, Landeo-Gutierrez J, Rhee KE, Ryu J, Kim C, Carmilani M, Gross RS, Mohandas S, Suresh S, Bailey LC, Castro V, Senathirajah Y, Esquenazi-Karonika S, Murphy S, Caddle S, Kleinman LC, Castro-Baucom L, Oliveira CR, Klein JD, Chung A, Cowell LG, Madlock-Brown C, Geary CR, Sills MR, Thorpe LE, Szmuszkovicz J, Tantisira KG; RECOVER EHR and; RECOVER Pediatric Cohorts. Rao S, et al. EClinicalMedicine. 2025 Jan 2;80:103042. doi: 10.1016/j.eclinm.2024.103042. eCollection 2025 Feb. EClinicalMedicine. 2025. PMID: 39850015 Free PMC article.
Integration of 168,000 samples reveals global patterns of the human gut microbiome.
Abdill RJ, Graham SP, Rubinetti V, Ahmadian M, Hicks P, Chetty A, McDonald D, Ferretti P, Gibbons E, Rossi M, Krishnan A, Albert FW, Greene CS, Davis S, Blekhman R. Abdill RJ, et al. Among authors: krishnan a. Cell. 2025 Jan 16:S0092-8674(24)01430-2. doi: 10.1016/j.cell.2024.12.017. Online ahead of print. Cell. 2025. PMID: 39848248 Free article.
2,053 results