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262 results

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A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers.
LaBelle JL, Katz SG, Bird GH, Gavathiotis E, Stewart ML, Lawrence C, Fisher JK, Godes M, Pitter K, Kung AL, Walensky LD. LaBelle JL, et al. Among authors: kung al. J Clin Invest. 2012 Jun;122(6):2018-31. doi: 10.1172/JCI46231. Epub 2012 May 24. J Clin Invest. 2012. PMID: 22622039 Free PMC article.
Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix.
Walensky LD, Kung AL, Escher I, Malia TJ, Barbuto S, Wright RD, Wagner G, Verdine GL, Korsmeyer SJ. Walensky LD, et al. Among authors: kung al. Science. 2004 Sep 3;305(5689):1466-70. doi: 10.1126/science.1099191. Science. 2004. PMID: 15353804 Free PMC article.
Therapeutic targeting of apoptosis pathways in cancer.
Ziegler DS, Kung AL. Ziegler DS, et al. Among authors: kung al. Curr Opin Oncol. 2008 Jan;20(1):97-103. doi: 10.1097/CCO.0b013e3282f310f6. Curr Opin Oncol. 2008. PMID: 18043263 Review.
A stapled p53 helix overcomes HDMX-mediated suppression of p53.
Bernal F, Wade M, Godes M, Davis TN, Whitehead DG, Kung AL, Wahl GM, Walensky LD. Bernal F, et al. Among authors: kung al. Cancer Cell. 2010 Nov 16;18(5):411-22. doi: 10.1016/j.ccr.2010.10.024. Cancer Cell. 2010. PMID: 21075307 Free PMC article.
The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia.
Banerji V, Frumm SM, Ross KN, Li LS, Schinzel AC, Hahn CK, Kakoza RM, Chow KT, Ross L, Alexe G, Tolliday N, Inguilizian H, Galinsky I, Stone RM, DeAngelo DJ, Roti G, Aster JC, Hahn WC, Kung AL, Stegmaier K. Banerji V, et al. Among authors: kung al. J Clin Invest. 2012 Mar;122(3):935-47. doi: 10.1172/JCI46465. Epub 2012 Feb 13. J Clin Invest. 2012. PMID: 22326953 Free PMC article.
Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia.
Kentsis A, Reed C, Rice KL, Sanda T, Rodig SJ, Tholouli E, Christie A, Valk PJ, Delwel R, Ngo V, Kutok JL, Dahlberg SE, Moreau LA, Byers RJ, Christensen JG, Vande Woude G, Licht JD, Kung AL, Staudt LM, Look AT. Kentsis A, et al. Among authors: kung al. Nat Med. 2012 Jul;18(7):1118-22. doi: 10.1038/nm.2819. Nat Med. 2012. PMID: 22683780 Free PMC article.
Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling.
Takada K, Zhu D, Bird GH, Sukhdeo K, Zhao JJ, Mani M, Lemieux M, Carrasco DE, Ryan J, Horst D, Fulciniti M, Munshi NC, Xu W, Kung AL, Shivdasani RA, Walensky LD, Carrasco DR. Takada K, et al. Among authors: kung al. Sci Transl Med. 2012 Aug 22;4(148):148ra117. doi: 10.1126/scitranslmed.3003808. Sci Transl Med. 2012. PMID: 22914623 Free PMC article.
262 results