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Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects.
Torgerson DG, Capurso D, Ampleford EJ, Li X, Moore WC, Gignoux CR, Hu D, Eng C, Mathias RA, Busse WW, Castro M, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Teague WG, Wenzel SE, Rodríguez-Santana JR, Rodríguez-Cintrón W, Avila PC, Ford JG, Barnes KC, Burchard EG, Howard TD, Bleecker ER, Meyers DA, Cox NJ, Ober C, Nicolae DL. Torgerson DG, et al. Among authors: israel e. J Allergy Clin Immunol. 2012 Sep;130(3):622-629.e9. doi: 10.1016/j.jaci.2012.03.045. Epub 2012 May 18. J Allergy Clin Immunol. 2012. PMID: 22607992 Free PMC article.
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.
Torgerson DG, Ampleford EJ, Chiu GY, Gauderman WJ, Gignoux CR, Graves PE, Himes BE, Levin AM, Mathias RA, Hancock DB, Baurley JW, Eng C, Stern DA, Celedón JC, Rafaels N, Capurso D, Conti DV, Roth LA, Soto-Quiros M, Togias A, Li X, Myers RA, Romieu I, Van Den Berg DJ, Hu D, Hansel NN, Hernandez RD, Israel E, Salam MT, Galanter J, Avila PC, Avila L, Rodriquez-Santana JR, Chapela R, Rodriguez-Cintron W, Diette GB, Adkinson NF, Abel RA, Ross KD, Shi M, Faruque MU, Dunston GM, Watson HR, Mantese VJ, Ezurum SC, Liang L, Ruczinski I, Ford JG, Huntsman S, Chung KF, Vora H, Li X, Calhoun WJ, Castro M, Sienra-Monge JJ, del Rio-Navarro B, Deichmann KA, Heinzmann A, Wenzel SE, Busse WW, Gern JE, Lemanske RF Jr, Beaty TH, Bleecker ER, Raby BA, Meyers DA, London SJ; Mexico City Childhood Asthma Study (MCAAS); Gilliland FD; Children's Health Study (CHS) and HARBORS study; Burchard EG; Genetics of Asthma in Latino Americans (GALA) Study, Study of Genes-Environment and Admixture in Latino Americans (GALA2) and Study of African Americans, Asthma, Genes & Environments (SAGE); Martinez FD; Childhood Asthma Research and Education (CARE) Network; Weiss ST; Childhood Asthma Management Program… See abstract for full author list ➔ Torgerson DG, et al. Among authors: israel e. Nat Genet. 2011 Jul 31;43(9):887-92. doi: 10.1038/ng.888. Nat Genet. 2011. PMID: 21804549 Free PMC article.
Importance of hedgehog interacting protein and other lung function genes in asthma.
Li X, Howard TD, Moore WC, Ampleford EJ, Li H, Busse WW, Calhoun WJ, Castro M, Chung KF, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Teague WG, Wenzel SE, Peters SP, Hawkins GA, Bleecker ER, Meyers DA. Li X, et al. Among authors: israel e. J Allergy Clin Immunol. 2011 Jun;127(6):1457-65. doi: 10.1016/j.jaci.2011.01.056. Epub 2011 Mar 12. J Allergy Clin Immunol. 2011. PMID: 21397937 Free PMC article.
Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases.
Li X, Ampleford EJ, Howard TD, Moore WC, Torgerson DG, Li H, Busse WW, Castro M, Erzurum SC, Israel E, Nicolae DL, Ober C, Wenzel SE, Hawkins GA, Bleecker ER, Meyers DA. Li X, et al. Among authors: israel e. J Allergy Clin Immunol. 2012 Oct;130(4):861-8.e7. doi: 10.1016/j.jaci.2012.04.041. Epub 2012 Jun 12. J Allergy Clin Immunol. 2012. PMID: 22694930 Free PMC article.
Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients.
Li X, Hawkins GA, Ampleford EJ, Moore WC, Li H, Hastie AT, Howard TD, Boushey HA, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Israel E, Lemanske RF Jr, Szefler SJ, Wasserman SI, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Li X, et al. Among authors: israel e. J Allergy Clin Immunol. 2013 Aug;132(2):313-20.e15. doi: 10.1016/j.jaci.2013.01.051. Epub 2013 Mar 28. J Allergy Clin Immunol. 2013. PMID: 23541324 Free PMC article.
Exacerbation-prone asthma in the context of race and ancestry in Asthma Clinical Research Network trials.
Grossman NL, Ortega VE, King TS, Bleecker ER, Ampleford EA, Bacharier LB, Cabana MD, Cardet JC, Carr TF, Castro M, Denlinger LC, Denson JL, Fandino N, Fitzpatrick AM, Hawkins GA, Holguin F, Krishnan JA, Lazarus SC, Nyenhuis SM, Phipatanakul W, Ramratnam SK, Wenzel S, Peters SP, Meyers DA, Wechsler ME, Israel E. Grossman NL, et al. Among authors: israel e. J Allergy Clin Immunol. 2019 Dec;144(6):1524-1533. doi: 10.1016/j.jaci.2019.08.033. Epub 2019 Sep 11. J Allergy Clin Immunol. 2019. PMID: 31520679 Free PMC article. Clinical Trial.
Genetic analyses identify GSDMB associated with asthma severity, exacerbations, and antiviral pathways.
Li X, Christenson SA, Modena B, Li H, Busse WW, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Hastie AT, Israel E, Jarjour NN, Levy BD, Moore WC, Woodruff PG, Kaminski N, Wenzel SE, Bleecker ER, Meyers DA; NHLBI Severe Asthma Research Program (SARP). Li X, et al. Among authors: israel e. J Allergy Clin Immunol. 2021 Mar;147(3):894-909. doi: 10.1016/j.jaci.2020.07.030. Epub 2020 Aug 11. J Allergy Clin Immunol. 2021. PMID: 32795586 Free PMC article.
Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.
Moore WC, Bleecker ER, Curran-Everett D, Erzurum SC, Ameredes BT, Bacharier L, Calhoun WJ, Castro M, Chung KF, Clark MP, Dweik RA, Fitzpatrick AM, Gaston B, Hew M, Hussain I, Jarjour NN, Israel E, Levy BD, Murphy JR, Peters SP, Teague WG, Meyers DA, Busse WW, Wenzel SE; National Heart, Lung, Blood Institute's Severe Asthma Research Program. Moore WC, et al. Among authors: israel e. J Allergy Clin Immunol. 2007 Feb;119(2):405-13. doi: 10.1016/j.jaci.2006.11.639. J Allergy Clin Immunol. 2007. PMID: 17291857 Free PMC article.
Racial differences in biologic predictors of severe asthma: Data from the Severe Asthma Research Program.
Gamble C, Talbott E, Youk A, Holguin F, Pitt B, Silveira L, Bleecker E, Busse W, Calhoun W, Castro M, Chung KF, Erzurum S, Israel E, Wenzel S. Gamble C, et al. Among authors: israel e. J Allergy Clin Immunol. 2010 Dec;126(6):1149-56.e1. doi: 10.1016/j.jaci.2010.08.049. Epub 2010 Nov 4. J Allergy Clin Immunol. 2010. PMID: 21051082 Free PMC article. Clinical Trial.
Obesity and asthma: an association modified by age of asthma onset.
Holguin F, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Moore WC, Peters SP, Yonas M, Teague WG, Wenzel SE. Holguin F, et al. Among authors: israel e. J Allergy Clin Immunol. 2011 Jun;127(6):1486-93.e2. doi: 10.1016/j.jaci.2011.03.036. J Allergy Clin Immunol. 2011. PMID: 21624618 Free PMC article.
696 results