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Mutation of the calmodulin binding motif IQ of the L-type Ca(v)1.2 Ca2+ channel to EQ induces dilated cardiomyopathy and death.
Blaich A, Pahlavan S, Tian Q, Oberhofer M, Poomvanicha M, Lenhardt P, Domes K, Wegener JW, Moosmang S, Ruppenthal S, Scholz A, Lipp P, Hofmann F. Blaich A, et al. Among authors: moosmang s. J Biol Chem. 2012 Jun 29;287(27):22616-25. doi: 10.1074/jbc.M112.357921. Epub 2012 May 15. J Biol Chem. 2012. PMID: 22589547 Free PMC article.
Mouse models to study L-type calcium channel function.
Moosmang S, Lenhardt P, Haider N, Hofmann F, Wegener JW. Moosmang S, et al. Pharmacol Ther. 2005 Jun;106(3):347-55. doi: 10.1016/j.pharmthera.2004.12.003. Pharmacol Ther. 2005. PMID: 15922017 Review.
47 results