Mach R - Search Results

1

Feasibility and dosimetry studies for 18F-NOS as a potential PET radiopharmaceutical for inducible nitric oxide synthase in humans.

Herrero P, Laforest R, Shoghi K, Zhou D, Ewald G, Pfeifer J, Duncavage E, Krupp K, Mach R, Gropler R. Herrero P, et al. Among authors: mach r. J Nucl Med. 2012 Jun;53(6):994-1001. doi: 10.2967/jnumed.111.088518. Epub 2012 May 11. J Nucl Med. 2012. PMID: 22582045 Free article.

2

Imaging myocardium enzymatic pathways with carbon-11 radiotracers.

Dence CS, Herrero P, Schwarz SW, Mach RH, Gropler RJ, Welch MJ. Dence CS, et al. Methods Enzymol. 2004;385:286-315. doi: 10.1016/S0076-6879(04)85016-X. Methods Enzymol. 2004. PMID: 15130745 Review. No abstract available.

3

Carbon-11 labeled sigma2 receptor ligands for imaging breast cancer.

Tu Z, Dence CS, Ponde DE, Jones L, Wheeler KT, Welch MJ, Mach RH. Tu Z, et al. Nucl Med Biol. 2005 Jul;32(5):423-30. doi: 10.1016/j.nucmedbio.2005.03.008. Nucl Med Biol. 2005. PMID: 15982571

4

Synthesis and in vivo evaluation of 2 high-affinity 76Br-labeled sigma2-receptor ligands.

Rowland DJ, Tu Z, Xu J, Ponde D, Mach RH, Welch MJ. Rowland DJ, et al. J Nucl Med. 2006 Jun;47(6):1041-8. J Nucl Med. 2006. PMID: 16741315 Free article.

5

Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis.

Zhou D, Chu W, Rothfuss J, Zeng C, Xu J, Jones L, Welch MJ, Mach RH. Zhou D, et al. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5041-6. doi: 10.1016/j.bmcl.2006.07.045. Epub 2006 Aug 7. Bioorg Med Chem Lett. 2006. PMID: 16891117

6

Isatin sulfonamide analogs containing a Michael addition acceptor: a new class of caspase 3/7 inhibitors.

Chu W, Rothfuss J, d'Avignon A, Zeng C, Zhou D, Hotchkiss RS, Mach RH. Chu W, et al. J Med Chem. 2007 Jul 26;50(15):3751-5. doi: 10.1021/jm070506t. Epub 2007 Jun 23. J Med Chem. 2007. PMID: 17585855

7

New N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl phenylcarbamate analogs as sigma2 receptor ligands: synthesis, in vitro characterization, and evaluation as PET imaging and chemosensitization agents.

Chu W, Xu J, Zhou D, Zhang F, Jones LA, Wheeler KT, Mach RH. Chu W, et al. Bioorg Med Chem. 2009 Feb 1;17(3):1222-31. doi: 10.1016/j.bmc.2008.12.025. Epub 2008 Dec 24. Bioorg Med Chem. 2009. PMID: 19119012 Free PMC article.

8

Synthesis and in vitro and in vivo evaluation of 18F-labeled positron emission tomography (PET) ligands for imaging the vesicular acetylcholine transporter.

Tu Z, Efange SM, Xu J, Li S, Jones LA, Parsons SM, Mach RH. Tu Z, et al. J Med Chem. 2009 Mar 12;52(5):1358-69. doi: 10.1021/jm8012344. J Med Chem. 2009. PMID: 19203271 Free PMC article.

9

[18F]- and [11C]-labeled N-benzyl-isatin sulfonamide analogues as PET tracers for apoptosis: synthesis, radiolabeling mechanism, and in vivo imaging study of apoptosis in Fas-treated mice using [11C]WC-98.

Zhou D, Chu W, Chen DL, Wang Q, Reichert DE, Rothfuss J, D'Avignon A, Welch MJ, Mach RH. Zhou D, et al. Org Biomol Chem. 2009 Apr 7;7(7):1337-48. doi: 10.1039/b819024k. Epub 2009 Feb 16. Org Biomol Chem. 2009. PMID: 19300818 Free PMC article.

10

Design and synthesis of 2-amino-4-methylpyridine analogues as inhibitors for inducible nitric oxide synthase and in vivo evaluation of [18F]6-(2-fluoropropyl)-4-methyl-pyridin-2-amine as a potential PET tracer for inducible nitric oxide synthase.

Zhou D, Lee H, Rothfuss JM, Chen DL, Ponde DE, Welch MJ, Mach RH. Zhou D, et al. J Med Chem. 2009 Apr 23;52(8):2443-53. doi: 10.1021/jm801556h. J Med Chem. 2009. PMID: 19323559 Free PMC article.

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