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Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-beta peptide exposure: involvement of Src family protein kinases.
Williamson R, Scales T, Clark BR, Gibb G, Reynolds CH, Kellie S, Bird IN, Varndell IM, Sheppard PW, Everall I, Anderton BH. Williamson R, et al. Among authors: reynolds ch. J Neurosci. 2002 Jan 1;22(1):10-20. doi: 10.1523/JNEUROSCI.22-01-00010.2002. J Neurosci. 2002. PMID: 11756483 Free PMC article.
Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway.
Killick R, Ribe EM, Al-Shawi R, Malik B, Hooper C, Fernandes C, Dobson R, Nolan PM, Lourdusamy A, Furney S, Lin K, Breen G, Wroe R, To AW, Leroy K, Causevic M, Usardi A, Robinson M, Noble W, Williamson R, Lunnon K, Kellie S, Reynolds CH, Bazenet C, Hodges A, Brion JP, Stephenson J, Simons JP, Lovestone S. Killick R, et al. Among authors: reynolds ch. Mol Psychiatry. 2014 Jan;19(1):88-98. doi: 10.1038/mp.2012.163. Epub 2012 Nov 20. Mol Psychiatry. 2014. PMID: 23164821 Free PMC article.
Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase.
Derkinderen P, Scales TM, Hanger DP, Leung KY, Byers HL, Ward MA, Lenz C, Price C, Bird IN, Perera T, Kellie S, Williamson R, Noble W, Van Etten RA, Leroy K, Brion JP, Reynolds CH, Anderton BH. Derkinderen P, et al. Among authors: reynolds ch. J Neurosci. 2005 Jul 13;25(28):6584-93. doi: 10.1523/JNEUROSCI.1487-05.2005. J Neurosci. 2005. PMID: 16014719 Free PMC article.
Tyrosine phosphorylation of tau by the SRC family kinases lck and fyn.
Scales TM, Derkinderen P, Leung KY, Byers HL, Ward MA, Price C, Bird IN, Perera T, Kellie S, Williamson R, Anderton BH, Reynolds CH. Scales TM, et al. Among authors: reynolds ch. Mol Neurodegener. 2011 Jan 26;6:12. doi: 10.1186/1750-1326-6-12. Mol Neurodegener. 2011. PMID: 21269457 Free PMC article.
109 results