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514 results

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Page 1
Discovery of a ZIP7 inhibitor from a Notch pathway screen.
Nolin E, Gans S, Llamas L, Bandyopadhyay S, Brittain SM, Bernasconi-Elias P, Carter KP, Loureiro JJ, Thomas JR, Schirle M, Yang Y, Guo N, Roma G, Schuierer S, Beibel M, Lindeman A, Sigoillot F, Chen A, Xie KX, Ho S, Reece-Hoyes J, Weihofen WA, Tyskiewicz K, Hoepfner D, McDonald RI, Guthrie N, Dogra A, Guo H, Shao J, Ding J, Canham SM, Boynton G, George EL, Kang ZB, Antczak C, Porter JA, Wallace O, Tallarico JA, Palmer AE, Jenkins JL, Jain RK, Bushell SM, Fryer CJ. Nolin E, et al. Among authors: loureiro jj. Nat Chem Biol. 2019 Feb;15(2):179-188. doi: 10.1038/s41589-018-0200-7. Epub 2019 Jan 14. Nat Chem Biol. 2019. PMID: 30643281 Free PMC article.
Benchmarking network algorithms for contextualizing genes of interest.
Hill A, Gleim S, Kiefer F, Sigoillot F, Loureiro J, Jenkins J, Morris MK. Hill A, et al. Among authors: loureiro j. PLoS Comput Biol. 2019 Dec 20;15(12):e1007403. doi: 10.1371/journal.pcbi.1007403. eCollection 2019 Dec. PLoS Comput Biol. 2019. PMID: 31860671 Free PMC article.
An iron-dependent metabolic vulnerability underlies VPS34-dependence in RKO cancer cells.
Kobylarz MJ, Goodwin JM, Kang ZB, Annand JW, Hevi S, O'Mahony E, McAllister G, Reece-Hoyes J, Wang Q, Alford J, Russ C, Lindeman A, Beibel M, Roma G, Carbone W, Knehr J, Loureiro J, Antczak C, Wiederschain D, Murphy LO, Menon S, Nyfeler B. Kobylarz MJ, et al. Among authors: loureiro j. PLoS One. 2020 Aug 24;15(8):e0235551. doi: 10.1371/journal.pone.0235551. eCollection 2020. PLoS One. 2020. PMID: 32833964 Free PMC article.
Non-invasive candidate protein signature predicts hepatic venous pressure gradient reduction in cirrhotic patients after sustained virologic response.
Richards SM, Guo F, Zou H, Nigsch F, Baiges A, Pachori A, Zhang Y, Lens S, Pitts R, Finkel N, Loureiro J, Mongeon D, Ma S, Watkins M, Polus F, Albillos A, Tellez L, Martinez-González J, Bañares R, Turon F, Ferrusquía-Acosta J, Perez-Campuzano V, Magaz M, Forns X, Badman M, Sailer AW, Ukomadu C, Hernández-Gea V, Garcia-Pagán JC. Richards SM, et al. Among authors: loureiro j. Liver Int. 2023 Sep;43(9):1984-1994. doi: 10.1111/liv.15657. Epub 2023 Jul 13. Liver Int. 2023. PMID: 37443448
A hypomorphic lsd1 allele results in heart development defects in mice.
Nicholson TB, Singh AK, Su H, Hevi S, Wang J, Bajko J, Li M, Valdez R, Goetschkes M, Capodieci P, Loureiro J, Cheng X, Li E, Kinzel B, Labow M, Chen T. Nicholson TB, et al. Among authors: loureiro j. PLoS One. 2013 Apr 24;8(4):e60913. doi: 10.1371/journal.pone.0060913. Print 2013. PLoS One. 2013. PMID: 23637775 Free PMC article.
mTORC1 signaling suppresses Wnt/β-catenin signaling through DVL-dependent regulation of Wnt receptor FZD level.
Zeng H, Lu B, Zamponi R, Yang Z, Wetzel K, Loureiro J, Mohammadi S, Beibel M, Bergling S, Reece-Hoyes J, Russ C, Roma G, Tchorz JS, Capodieci P, Cong F. Zeng H, et al. Among authors: loureiro j. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10362-E10369. doi: 10.1073/pnas.1808575115. Epub 2018 Oct 8. Proc Natl Acad Sci U S A. 2018. PMID: 30297426 Free PMC article.
The Genetic Architecture of Carbon Tetrachloride-Induced Liver Fibrosis in Mice.
Tuominen I, Fuqua BK, Pan C, Renaud N, Wroblewski K, Civelek M, Clerkin K, Asaryan A, Haroutunian SG, Loureiro J, Borawski J, Roma G, Knehr J, Carbone W, French S, Parks BW, Hui ST, Mehrabian M, Magyar C, Cantor RM, Ukomadu C, Lusis AJ, Beaven SW. Tuominen I, et al. Among authors: loureiro j. Cell Mol Gastroenterol Hepatol. 2021;11(1):199-220. doi: 10.1016/j.jcmgh.2020.08.010. Epub 2020 Aug 28. Cell Mol Gastroenterol Hepatol. 2021. PMID: 32866618 Free PMC article.
Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury.
Larraufie MH, Gao X, Xia X, Devine PJ, Kallen J, Liu D, Michaud G, Harsch A, Savage N, Ding J, Tan K, Mihalic M, Roggo S, Canham SM, Bushell SM, Krastel P, Gao J, Izaac A, Altinoglu E, Lustenberger P, Salcius M, Harbinski F, Williams ET, Zeng L, Loureiro J, Cong F, Fryer CJ, Klickstein L, Tallarico JA, Jain RK, Rothman DM, Wang S. Larraufie MH, et al. Among authors: loureiro j. Cell Chem Biol. 2021 Sep 16;28(9):1271-1282.e12. doi: 10.1016/j.chembiol.2021.04.001. Epub 2021 Apr 23. Cell Chem Biol. 2021. PMID: 33894161 Free article.
514 results