Metzker ML - Search Results

1

Rapid incorporation kinetics and improved fidelity of a novel class of 3'-OH unblocked reversible terminators.

Gardner AF, Wang J, Wu W, Karouby J, Li H, Stupi BP, Jack WE, Hersh MN, Metzker ML. Gardner AF, et al. Among authors: metzker ml. Nucleic Acids Res. 2012 Aug;40(15):7404-15. doi: 10.1093/nar/gks330. Epub 2012 May 8. Nucleic Acids Res. 2012. PMID: 22570423 Free PMC article.

2

Improved nucleotide selectivity and termination of 3'-OH unblocked reversible terminators by molecular tuning of 2-nitrobenzyl alkylated HOMedU triphosphates.

Litosh VA, Wu W, Stupi BP, Wang J, Morris SE, Hersh MN, Metzker ML. Litosh VA, et al. Among authors: metzker ml. Nucleic Acids Res. 2011 Mar;39(6):e39. doi: 10.1093/nar/gkq1293. Epub 2011 Jan 11. Nucleic Acids Res. 2011. PMID: 21227920 Free PMC article.

3

Termination of DNA synthesis by N6-alkylated, not 3'-O-alkylated, photocleavable 2'-deoxyadenosine triphosphates.

Wu W, Stupi BP, Litosh VA, Mansouri D, Farley D, Morris S, Metzker S, Metzker ML. Wu W, et al. Among authors: metzker s, metzker ml. Nucleic Acids Res. 2007;35(19):6339-49. doi: 10.1093/nar/gkm689. Epub 2007 Sep 18. Nucleic Acids Res. 2007. PMID: 17881370 Free PMC article.

4

Stereochemistry of benzylic carbon substitution coupled with ring modification of 2-nitrobenzyl groups as key determinants for fast-cleaving reversible terminators.

Stupi BP, Li H, Wang J, Wu W, Morris SE, Litosh VA, Muniz J, Hersh MN, Metzker ML. Stupi BP, et al. Among authors: metzker ml. Angew Chem Int Ed Engl. 2012 Feb 13;51(7):1724-7. doi: 10.1002/anie.201106516. Epub 2012 Jan 9. Angew Chem Int Ed Engl. 2012. PMID: 22231919 Free PMC article. No abstract available.

5

Termination of DNA synthesis by novel 3'-modified-deoxyribonucleoside 5'-triphosphates.

Metzker ML, Raghavachari R, Richards S, Jacutin SE, Civitello A, Burgess K, Gibbs RA. Metzker ML, et al. Nucleic Acids Res. 1994 Oct 11;22(20):4259-67. doi: 10.1093/nar/22.20.4259. Nucleic Acids Res. 1994. PMID: 7937154 Free PMC article.

6

Emerging technologies in DNA sequencing.

Metzker ML. Metzker ML. Genome Res. 2005 Dec;15(12):1767-76. doi: 10.1101/gr.3770505. Genome Res. 2005. PMID: 16339375 Free article. Review.

7

A-beta-subtype of ketosis-prone diabetes is not predominantly a monogenic diabetic syndrome.

Haaland WC, Scaduto DI, Maldonado MR, Mansouri DL, Nalini R, Iyer D, Patel S, Guthikonda A, Hampe CS, Balasubramanyam A, Metzker ML. Haaland WC, et al. Among authors: metzker ml. Diabetes Care. 2009 May;32(5):873-7. doi: 10.2337/dc08-1529. Epub 2009 Feb 19. Diabetes Care. 2009. PMID: 19228875 Free PMC article.

8

Accurate determination of DNA in agarose gels using the novel algorithm GelScann(1.0).

Metzker ML, Allain KM, Gibbs RA. Metzker ML, et al. Comput Appl Biosci. 1995 Apr;11(2):187-94. doi: 10.1093/bioinformatics/11.2.187. Comput Appl Biosci. 1995. PMID: 7620992

9

Electrophoretically uniform fluorescent dyes for automated DNA sequencing.

Metzker ML, Lu J, Gibbs RA. Metzker ML, et al. Science. 1996 Mar 8;271(5254):1420-2. doi: 10.1126/science.271.5254.1420. Science. 1996. PMID: 8596915

10

Shotgun sample sequence comparisons between mouse and human genomes.

Bouck JB, Metzker ML, Gibbs RA. Bouck JB, et al. Among authors: metzker ml. Nat Genet. 2000 May;25(1):31-3. doi: 10.1038/75563. Nat Genet. 2000. PMID: 10802652

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