Lang MJ - Search Results

1

TCR Mechanobiology: Torques and Tunable Structures Linked to Early T Cell Signaling.

Kim ST, Shin Y, Brazin K, Mallis RJ, Sun ZY, Wagner G, Lang MJ, Reinherz EL. Kim ST, et al. Among authors: lang mj. Front Immunol. 2012 Apr 18;3:76. doi: 10.3389/fimmu.2012.00076. eCollection 2012. Front Immunol. 2012. PMID: 22566957 Free PMC article.

2

The alphabeta T cell receptor is an anisotropic mechanosensor.

Kim ST, Takeuchi K, Sun ZY, Touma M, Castro CE, Fahmy A, Lang MJ, Wagner G, Reinherz EL. Kim ST, et al. Among authors: lang mj. J Biol Chem. 2009 Nov 6;284(45):31028-37. doi: 10.1074/jbc.M109.052712. Epub 2009 Sep 15. J Biol Chem. 2009. PMID: 19755427 Free PMC article.

3

Stochastic optical active rheology.

Lee H, Shin Y, Kim ST, Reinherz EL, Lang MJ. Lee H, et al. Among authors: lang mj. Appl Phys Lett. 2012 Jul 16;101(3):31902. doi: 10.1063/1.4737159. Epub 2012 Jul 17. Appl Phys Lett. 2012. PMID: 22893729 Free PMC article.

4

Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime.

Das DK, Feng Y, Mallis RJ, Li X, Keskin DB, Hussey RE, Brady SK, Wang JH, Wagner G, Reinherz EL, Lang MJ. Das DK, et al. Among authors: lang mj. Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1517-22. doi: 10.1073/pnas.1424829112. Epub 2015 Jan 20. Proc Natl Acad Sci U S A. 2015. PMID: 25605925 Free PMC article.

5

Biased Brownian motion as a mechanism to facilitate nanometer-scale exploration of the microtubule plus end by a kinesin-8.

Shin Y, Du Y, Collier SE, Ohi MD, Lang MJ, Ohi R. Shin Y, et al. Among authors: lang mj. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3826-35. doi: 10.1073/pnas.1500272112. Epub 2015 Jul 6. Proc Natl Acad Sci U S A. 2015. PMID: 26150501 Free PMC article.

6

Structural Features of the αβTCR Mechanotransduction Apparatus That Promote pMHC Discrimination.

Brazin KN, Mallis RJ, Das DK, Feng Y, Hwang W, Wang JH, Wagner G, Lang MJ, Reinherz EL. Brazin KN, et al. Among authors: lang mj. Front Immunol. 2015 Sep 3;6:441. doi: 10.3389/fimmu.2015.00441. eCollection 2015. Front Immunol. 2015. PMID: 26388869 Free PMC article. Review.

7

Pre-T Cell Receptors (Pre-TCRs) Leverage Vβ Complementarity Determining Regions (CDRs) and Hydrophobic Patch in Mechanosensing Thymic Self-ligands.

Das DK, Mallis RJ, Duke-Cohan JS, Hussey RE, Tetteh PW, Hilton M, Wagner G, Lang MJ, Reinherz EL. Das DK, et al. Among authors: lang mj. J Biol Chem. 2016 Dec 2;291(49):25292-25305. doi: 10.1074/jbc.M116.752865. Epub 2016 Oct 5. J Biol Chem. 2016. PMID: 27707880 Free PMC article.

8

Mechanosensing drives acuity of αβ T-cell recognition.

Feng Y, Brazin KN, Kobayashi E, Mallis RJ, Reinherz EL, Lang MJ. Feng Y, et al. Among authors: lang mj. Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):E8204-E8213. doi: 10.1073/pnas.1703559114. Epub 2017 Aug 15. Proc Natl Acad Sci U S A. 2017. PMID: 28811364 Free PMC article.

9

NMR-directed design of pre-TCRβ and pMHC molecules implies a distinct geometry for pre-TCR relative to αβTCR recognition of pMHC.

Mallis RJ, Arthanari H, Lang MJ, Reinherz EL, Wagner G. Mallis RJ, et al. Among authors: lang mj. J Biol Chem. 2018 Jan 19;293(3):754-766. doi: 10.1074/jbc.M117.813493. Epub 2017 Nov 3. J Biol Chem. 2018. PMID: 29101227 Free PMC article.

10

αβ T Cell Receptor Mechanosensing Forces out Serial Engagement.

Feng Y, Reinherz EL, Lang MJ. Feng Y, et al. Among authors: lang mj. Trends Immunol. 2018 Aug;39(8):596-609. doi: 10.1016/j.it.2018.05.005. Epub 2018 Jul 4. Trends Immunol. 2018. PMID: 30060805 Free PMC article. Review.

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