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Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis.
Castaño Betancourt MC, Cailotto F, Kerkhof HJ, Cornelis FM, Doherty SA, Hart DJ, Hofman A, Luyten FP, Maciewicz RA, Mangino M, Metrustry S, Muir K, Peters MJ, Rivadeneira F, Wheeler M, Zhang W, Arden N, Spector TD, Uitterlinden AG, Doherty M, Lories RJ, Valdes AM, van Meurs JB. Castaño Betancourt MC, et al. Among authors: zhang w. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8218-23. doi: 10.1073/pnas.1119899109. Epub 2012 May 7. Proc Natl Acad Sci U S A. 2012. PMID: 22566624 Free PMC article.
Are joints affected by gout also affected by osteoarthritis?
Roddy E, Zhang W, Doherty M. Roddy E, et al. Among authors: zhang w. Ann Rheum Dis. 2007 Oct;66(10):1374-7. doi: 10.1136/ard.2006.063768. Epub 2007 Feb 6. Ann Rheum Dis. 2007. PMID: 17284542 Free PMC article.
The changing epidemiology of gout.
Roddy E, Zhang W, Doherty M. Roddy E, et al. Among authors: zhang w. Nat Clin Pract Rheumatol. 2007 Aug;3(8):443-9. doi: 10.1038/ncprheum0556. Nat Clin Pract Rheumatol. 2007. PMID: 17664951 Review.
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